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Information on EC 1.13.11.18 - persulfide dioxygenase and Organism(s) Arabidopsis thaliana and UniProt Accession Q9C8L4

for references in articles please use BRENDA:EC1.13.11.18
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EC Tree
IUBMB Comments
An iron protein. Perthiols, formed spontaneously by interactions between thiols and elemental sulfur or sulfide, are the only acceptable substrate to the enzyme. The sulfite that is formed by the enzyme can be further converted into sulfate, thiosulfate or S-sulfoglutathione (GSSO3-) non-enzymically .
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This record set is specific for:
Arabidopsis thaliana
UNIPROT: Q9C8L4
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Word Map
The taxonomic range for the selected organisms is: Arabidopsis thaliana
The expected taxonomic range for this enzyme is: Archaea, Bacteria, Eukaryota
Reaction Schemes
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Synonyms
sdo, ethe1, sulfur dioxygenase, persulfide dioxygenase, sulfur oxygenase, afe_0269, fe(ii)-containing persulfide dioxygenase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
sulfur dioxygenase
-
sulfur oxygenase
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
redox reaction
-
-
-
-
oxidation
-
-
-
-
reduction
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
S-sulfanylglutathione:oxygen oxidoreductase
An iron protein. Perthiols, formed spontaneously by interactions between thiols and elemental sulfur or sulfide, are the only acceptable substrate to the enzyme. The sulfite that is formed by the enzyme can be further converted into sulfate, thiosulfate or S-sulfoglutathione (GSSO3-) non-enzymically [2].
CAS REGISTRY NUMBER
COMMENTARY hide
37256-58-9
-
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
additional information
?
-
Arabidopsis ETHE1 catalyzes the glutathione persulfide-dependent consumption of oxygen
-
-
?
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
additional information
?
-
Arabidopsis ETHE1 catalyzes the glutathione persulfide-dependent consumption of oxygen
-
-
?
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
7.95
recombinant enzyme, pH and temperature not specified in the publication
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
additional information
no activity in the cytosol
-
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
seeds homozygous for a DNA insertion in ETHE1 exhibit alterations in endosperm development that are accompanied by a delay in embryo development followed by embryo arrest by early heart stage
physiological function
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
ETHE1_ARATH
294
0
32332
Swiss-Prot
Mitochondrion (Reliability: 4)
PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
generation of a ETHE1 loss-of-function mutation by DNA insertion, phenotpe overview
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
recombinant enzyme from Escherichia coli
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
gene ethe1, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic tree, expression in Escherichia coli
EXPRESSION
ORGANISM
UNIPROT
LITERATURE
expression is strongly induced by extended darkness
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Holdorf, M.M.; Owen, H.A.; Lieber, S.R.; Yuan, L.; Adams, N.; Dabney-Smith, C.; Makaroff, C.A.
Arabidopsis ETHE1 encodes a sulfur dioxygenase that is essential for embryo and endosperm development
Plant Physiol.
160
226-236
2012
Arabidopsis thaliana (Q9C8L4)
Manually annotated by BRENDA team
Lorenz, C.; Brandt, S.; Borisjuk, L.; Rolletschek, H.; Heinzel, N.; Tohge, T.; Fernie, A.R.; Braun, H.P.; Hildebrandt, T.M.
The role of persulfide metabolism during Arabidopsis seed development under light and dark conditions
Front. Plant Sci.
9
1381
2018
Arabidopsis thaliana (Q9C8L4), Arabidopsis thaliana
Manually annotated by BRENDA team