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Information on EC 1.13.11.12 - linoleate 13S-lipoxygenase

for references in articles please use BRENDA:EC1.13.11.12
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IUBMB Comments
Contains nonheme iron. A common plant lipoxygenase that oxidizes linoleate and alpha-linolenate, the two most common polyunsaturated fatty acids in plants, by inserting molecular oxygen at the C-13 position with (S)-configuration. This enzyme produces precursors for several important compounds, including the plant hormone jasmonic acid. EC 1.13.11.58, linoleate 9S-lipoxygenase, catalyses a similar reaction at the second available position of these fatty acids.
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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
(13S)-lipoxygenase, 13-lipoxygenase, 13-LOX, 13S-lipoxygenase, 15-lipoxygenase-1, 15-LOX-1, 9/13-LOX, AtLOX-2, AtLOX-3, AtLOX-4, more
REACTION
REACTION DIAGRAM
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ORGANISM
UNIPROT
LITERATURE
alpha-linolenate + O2 = (9Z,11E,13S,15Z)-13-hydroperoxyoctadeca-9,11,15-trienoate
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(2)
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linoleate + O2 = (9Z,11E,13S)-13-hydroperoxyoctadeca-9,11-dienoate
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; (1)
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