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Information on EC 1.11.1.19 - dye decolorizing peroxidase and Organism(s) Thermobifida fusca and UniProt Accession Q47KB1

for references in articles please use BRENDA:EC1.11.1.19
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EC Tree
     1 Oxidoreductases
         1.11 Acting on a peroxide as acceptor
             1.11.1 Peroxidases
                1.11.1.19 dye decolorizing peroxidase
IUBMB Comments
Heme proteins with proximal histidine secreted by basidiomycetous fungi and eubacteria. They are similar to EC 1.11.1.16 versatile peroxidase (oxidation of Reactive Black 5, phenols, veratryl alcohol), but differ from the latter in their ability to efficiently oxidize a number of recalcitrant anthraquinone dyes, and inability to oxidize Mn(II). The model substrate Reactive Blue 5 is converted with high efficiency via a so far unique mechanism that combines oxidative and hydrolytic steps and leads to the formation of phthalic acid. Bacterial TfuDyP catalyses sulfoxidation.
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This record set is specific for:
Thermobifida fusca
UNIPROT: Q47KB1
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Word Map
The taxonomic range for the selected organisms is: Thermobifida fusca
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
dye-decolorizing peroxidase, dyp-type peroxidase, dyp1b, tt1485, dye decolorizing peroxidase, lip ba45, mnp ba30, lip-sn, ancdypd-b1, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
dye-decolorizing peroxidase
DyP-type peroxidase
reactiveblue-5: hydrogen-peroxide oxidoreductase
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-
SYSTEMATIC NAME
IUBMB Comments
Reactive-Blue-5:hydrogen-peroxide oxidoreductase
Heme proteins with proximal histidine secreted by basidiomycetous fungi and eubacteria. They are similar to EC 1.11.1.16 versatile peroxidase (oxidation of Reactive Black 5, phenols, veratryl alcohol), but differ from the latter in their ability to efficiently oxidize a number of recalcitrant anthraquinone dyes, and inability to oxidize Mn(II). The model substrate Reactive Blue 5 is converted with high efficiency via a so far unique mechanism that combines oxidative and hydrolytic steps and leads to the formation of phthalic acid. Bacterial TfuDyP catalyses sulfoxidation.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) + H2O2
?
show the reaction diagram
-
-
-
-
?
2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) + H2O2 + H+
oxidized 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) + H2O
show the reaction diagram
-
-
-
?
2,6-dimethoxyphenol + H2O2
?
show the reaction diagram
-
-
-
-
?
Acid Blue 129 + H2O2 + H+
?
show the reaction diagram
-
-
-
-
?
Acid Blue 129 + H2O2 + H+
oxidized Acid Blue 129 + ? + H2O
show the reaction diagram
-
-
-
-
?
Acid Blue 80 + H2O2 + H+
?
show the reaction diagram
-
-
-
-
?
Acid Blue 9 + H2O2 + H+
?
show the reaction diagram
-
-
-
-
?
Acid Blue 93 + H2O2 + H+
?
show the reaction diagram
-
-
-
-
?
Acid Green 50 + H2O2 + H+
?
show the reaction diagram
-
-
-
-
?
Acid Orange 7 + H2O2 + H+
?
show the reaction diagram
-
-
-
-
?
Acid Red 14 + H2O2 + H+
?
show the reaction diagram
-
-
-
-
?
Acid Red 18 + H2O2 + H+
?
show the reaction diagram
-
-
-
-
?
adlerol + H2O2
?
show the reaction diagram
-
-
-
-
?
Basic Yellow 2 + H2O2 + H+
?
show the reaction diagram
-
-
-
-
?
beta,beta-carotene + H2O2 + H+
beta-ionone + beta-apo-10'-carotenal + H2O
show the reaction diagram
-
-
-
-
?
carminic acid + H2O2 + H+
?
show the reaction diagram
-
-
-
-
?
Cibacron Blue + H2O2 + H+
?
show the reaction diagram
-
-
-
-
?
copper phthalocyanine-3,4',4',4'''-tetrasulfonic acid + H2O2 + H+
?
show the reaction diagram
-
-
-
-
?
crocetin + H2O2 + H+
oxidized crocetin + ? + H2O
show the reaction diagram
-
-
-
-
?
crocin + H2O2 + H+
?
show the reaction diagram
-
-
-
-
?
Crystal Violet + H2O2 + H+
?
show the reaction diagram
-
-
-
-
?
curcumin + H2O2 + H+
?
show the reaction diagram
-
-
-
-
?
Direct Red 80 + H2O2 + H+
?
show the reaction diagram
-
-
-
-
?
Disperse Blue 1 + H2O2 + H+
?
show the reaction diagram
-
-
-
-
?
Eosin Y + H2O2 + H+
?
show the reaction diagram
-
-
-
-
?
Eosin Y + H2O2 + H+
oxidized Eosin Y + ? + H2O
show the reaction diagram
-
-
-
-
?
fluorescein + H2O2 + H+
?
show the reaction diagram
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-
-
-
?
Indigo Carmine + H2O2 + H+
?
show the reaction diagram
-
-
-
-
?
indigotetrasulfonate + H2O2 + H+
?
show the reaction diagram
-
-
-
-
?
Reactive Black 5 + H2O2 + H+
?
show the reaction diagram
-
-
-
-
?
Reactive Blue 14 + H2O2 + H+
oxidized Reactive Blue 14 + ? + H2O
show the reaction diagram
-
-
-
-
?
Reactive Blue 19 + H2O2 + H+
?
show the reaction diagram
-
-
-
-
?
Reactive Blue 19 + H2O2 + H+
oxidized Reactive Blue 19 + ? + H2O
show the reaction diagram
-
-
-
-
?
Reactive Blue 4 + H2O2 + H+
?
show the reaction diagram
-
-
-
-
?
Reactive Blue 5 + 2 H2O2
phthalate + 2,2'-disulfonyl azobenzene + 3-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]benzenesulfonate + 2 H2O
show the reaction diagram
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-
-
-
?
Reactive Blue 5 + H2O2 + H+
? + phthalic acid + H2O
show the reaction diagram
-
-
-
-
?
Reactive Red 120 + H2O2 + H+
?
show the reaction diagram
-
-
-
-
?
Reactive Red 2 + H2O2 + H+
?
show the reaction diagram
-
-
-
-
?
rhodamine B + H2O2 + H+
?
show the reaction diagram
-
-
-
-
?
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
Reactive Blue 5 + 2 H2O2
phthalate + 2,2'-disulfonyl azobenzene + 3-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]benzenesulfonate + 2 H2O
show the reaction diagram
-
-
-
-
?
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Mn2+
-
Mn2+ can improve the catalytic efficiency of the enzyme
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
UniProt
Manually annotated by BRENDA team
POSTTRANSLATIONAL MODIFICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
glycoprotein
-
-
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
Ni-Sepharose column chromatography
-
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expressed in Escherichia coli BL21(DE3) cells
expressed in Escherichia coli Top10 cells
-
APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
degradation
-
degradation of lignin derivatives
additional information
-
DyP-type peroxidases are interesting for applications in the waste treatment sector
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Hofrichter, M.; Ullrich, R.; Pecyna, M.J.; Liers, C.; Lundell, T.
New and classic families of secreted fungal heme peroxidases
Appl. Microbiol. Biotechnol.
87
871-897
2010
Anabaena sp., Auricularia auricula-judae, Bacillus subtilis, Bacteroides thetaiotaomicron, Escherichia coli, Mycetinis scorodonius, Shewanella oneidensis, Termitomyces albuminosus, Thanatephorus cucumeris, Thermobifida fusca
Manually annotated by BRENDA team
Loncar, N.; Colpa, D.; Fraaije, M.
Exploring the biocatalytic potential of a DyP-type peroxidase by profiling the substrate acceptance of Thermobifida fusca DyP peroxidase
Tetrahedron
72
7276-7281
2016
Thermobifida fusca
-
Manually annotated by BRENDA team
Feng, C.; Pan, M.; Tang, L.
5-Aminolevulinic acid level and dye-decolorizing peroxidase expression regulate heme synthesis in Escherichia coli
Biotechnol. Lett.
44
271-277
2022
Thermobifida fusca (Q47KB1)
Manually annotated by BRENDA team
Xu, L.; Sun, J.; Qaria, M.; Gao, L.; Zhu, D.
Dye decoloring peroxidase structure, catalytic properties and applications Current advancement and futurity
Catalysts
11
955
2021
Bacillus subtilis, Bacillus subtilis 168, Pleurotus sapidus, Saccharomonospora viridis, Thermobifida fusca, Thermomonospora curvata
-
Manually annotated by BRENDA team