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Synonyms
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flavin adenine dinucleotide-dependent 4-phospho-D-erythronate dehydrogenase
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pdxR-encoded 4PE dehydrogenase
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4-phospho-D-erythronate + FAD = 3-hydroxy-2-oxo-4-(phosphonooxy)butanoate + FADH2
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4-phospho-D-erythronate:FAD 3-oxidoreductase
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4-phospho-D-erythronate + 2,6-dichloroindophenol
3-hydroxy-4-phosphohydroxy-alpha-ketobutyrate + reduced 2,6-dichloroindophenol
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Substrates: -
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4-phospho-D-erythronate + FAD
3-hydroxy-4-phosphohydroxy-alpha-ketobutyrate + FADH2
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Substrates: -
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0.946
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0.091 mM DCIP and 0.00024 mg purified enzyme in 33 mM potassium phosphate buffer at pH 7.0
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formerly Rhizobium meliloti, strain IFO 14782
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brenda
Highest Expressing Human Cell Lines
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106000
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gel filtration chromatography
53190
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predicted from the pdxR DNA sequence
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homodimer
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2 * 53000, SDS-PAGE
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Q Sepharose FF column chromatography and Sephadex LH 20 column chromatography
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Tazoe, M.; Ichikawa, K.; Hoshino, T.
Flavin adenine dinucleotide-dependent 4-phospho-D-erythronate dehydrogenase is responsible for the 4-phosphohydroxy-L-threonine pathway in vitamin B6 biosynthesis in Sinorhizobium meliloti
J. Bacteriol.
188
4635-4645
2006
Sinorhizobium meliloti
brenda
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