HOME
login
history
all enzymes
BRENDA home
History
Enzyme Nomenclature
Information on EC 1.1.99.4 - dehydrogluconate dehydrogenase
for references in articles please use BRENDA:EC1.1.99.4Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Specify your search results
The enzyme appears in viruses and cellular organisms
topPlease wait a moment until the data is sorted. This message will disappear when the data is sorted.
EC NUMBER 
COMMENTARY 
1.1.99.4
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
RECOMMENDED NAME
GeneOntology No.
dehydrogluconate dehydrogenase
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT
LITERATURE
2-dehydro-D-gluconate + acceptor = 2,5-didehydro-D-gluconate + reduced acceptor
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
oxidation
-
-
-
-
redox reaction
-
-
-
-
reduction
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SYSTEMATIC NAME
IUBMB Comments
2-dehydro-D-gluconate:acceptor 2-oxidoreductase
A flavoprotein.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
CAS REGISTRY NUMBER
COMMENTARY
9028-82-4
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
cytochrome c subunit and large subunit and small subunit
A0A0B6VQG4, A0A0B6VN56, A0A0B6VKP6
UniProt
cytochrome c subunit and large subunit and small subunit
A0A0B6VQG4, A0A0B6VN56, A0A0B6VKP6
UniProt
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
2-dehydro-D-gluconate + methylene blue
2,5-didehydro-D-gluconate + ?
-
methylene blue is not as effective as 2,6-dichlorophenolindophenol
-
-
?
2-dehydro-D-gluconate + nitro blue tetrazolium
2,5-didehydro-D-gluconate + ?
-
-
-
-
?
2-dehydro-D-gluconate + phenazine methosulfate
2,5-didehydro-D-gluconate + ?
-
-
-
-
?
2-dehydro-D-gluconate + pyocyanine
2,5-didehydro-D-gluconate + ?
-
pyocyanine is not as effective as 2,6-dichlorophenolindophenol
-
-
?
2-dehydro-D-gluconate + 2,6-dichlorophenolindophenol
2,5-didehydro-D-gluconate + ?
-
-
-
-
?
2-dehydro-D-gluconate + 2,6-dichlorophenolindophenol
2,5-didehydro-D-gluconate + ?
-
-
-
-
?
2-dehydro-D-gluconate + 2,6-dichlorophenolindophenol
2,5-didehydro-D-gluconate + ?
-
-
-
-
?
2-dehydro-D-gluconate + 2,6-dichlorophenolindophenol
2,5-didehydro-D-gluconate + ?
-
-
-
-
?
2-dehydro-D-gluconate + acceptor
?
-
enzyme of the D-glucose oxidation pathway
-
-
?
2-dehydro-D-gluconate + acceptor
?
-
enzyme is the primary dehydrogenase of the 2-keto-D-gluconate oxidizing system
-
-
?
2-dehydro-D-gluconate + acceptor
?
-
enzyme of the D-glucose oxidation pathway
-
-
?
2-dehydro-D-gluconate + acceptor
?
-
enzyme of the D-glucose oxidation pathway
-
-
?
2-dehydro-D-gluconate + acceptor
?
-
enzyme of the D-glucose oxidation pathway
-
-
?
2-dehydro-D-gluconate + acceptor
?
-
enzyme of the D-glucose oxidation pathway
-
-
?
2-dehydro-D-gluconate + acceptor
?
-
enzyme of the D-glucose oxidation pathway
-
-
?
2-dehydro-D-gluconate + acceptor
?
-
enzyme of the D-glucose oxidation pathway
-
-
?
2-dehydro-D-gluconate + acceptor
?
-
enzyme of the D-glucose oxidation pathway
-
-
?
2-dehydro-D-gluconate + ferricyanide
2,5-didehydro-D-gluconate + ferrocyanide
-
-
-
-
?
2-dehydro-D-gluconate + ferricyanide
2,5-didehydro-D-gluconate + ferrocyanide
A0A0B6VQG4; A0A0B6VN56; A0A0B6VKP6;
-
-
-
?
2-dehydro-D-gluconate + ferricyanide
2,5-didehydro-D-gluconate + ferrocyanide
A0A0B6VQG4; A0A0B6VN56; A0A0B6VKP6;
-
-
-
?
2-dehydro-D-gluconate + ferricyanide
2,5-didehydro-D-gluconate + ferrocyanide
-
-
-
-
?
additional information
?
-
A0A0B6VQG4; A0A0B6VN56; A0A0B6VKP6;
the enzyme is completely inert toward 5-oxoglutarate, D-gluconate, D-glucose, D-sorbitol, L-lactate, L-malate, and D-fructose
-
-
-
additional information
?
-
-
the enzyme is completely inert toward 5-oxoglutarate, D-gluconate, D-glucose, D-sorbitol, L-lactate, L-malate, and D-fructose
-
-
-
additional information
?
-
A0A0B6VQG4; A0A0B6VN56; A0A0B6VKP6;
the enzyme is completely inert toward 5-oxoglutarate, D-gluconate, D-glucose, D-sorbitol, L-lactate, L-malate, and D-fructose
-
-
-
additional information
?
-
-
the enzyme is completely inert toward 5-oxoglutarate, D-gluconate, D-glucose, D-sorbitol, L-lactate, L-malate, and D-fructose
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
2-dehydro-D-gluconate + acceptor
?
-
enzyme of the D-glucose oxidation pathway
-
-
?
2-dehydro-D-gluconate + acceptor
?
-
enzyme is the primary dehydrogenase of the 2-keto-D-gluconate oxidizing system
-
-
?
2-dehydro-D-gluconate + acceptor
?
-
enzyme of the D-glucose oxidation pathway
-
-
?
2-dehydro-D-gluconate + acceptor
?
-
enzyme of the D-glucose oxidation pathway
-
-
?
2-dehydro-D-gluconate + acceptor
?
-
enzyme of the D-glucose oxidation pathway
-
-
?
2-dehydro-D-gluconate + acceptor
?
-
enzyme of the D-glucose oxidation pathway
-
-
?
2-dehydro-D-gluconate + acceptor
?
-
enzyme of the D-glucose oxidation pathway
-
-
?
2-dehydro-D-gluconate + acceptor
?
-
enzyme of the D-glucose oxidation pathway
-
-
?
2-dehydro-D-gluconate + acceptor
?
-
enzyme of the D-glucose oxidation pathway
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
COFACTOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
cytochrome
-
contains 0.91 mol of tightly bound c-type cytochrome per mol of enzyme
-
flavin
-
contains 8alpha-(N3-histidyl) riboflavin in the dinucleotide form; flavoprotein
flavin
-
contains 0.44 mol of covalently bound flavin per mol of enzyme; flavoprotein
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
INHIBITORS
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY
GeneOntology No.
LITERATURE
SOURCE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
25000
-
1 * 61000, flavoprotein + 1 * 47000, cytochrome component, + 1 * 25000, function unclear, SDS-PAGE
47000
-
1 * 61000, flavoprotein + 1 * 47000, cytochrome component, + 1 * 25000, function unclear, SDS-PAGE
61000
-
1 * 61000, flavoprotein + 1 * 47000, cytochrome component, + 1 * 25000, function unclear, SDS-PAGE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SUBUNITS
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
trimer
trimer
-
1 * 61000, flavoprotein + 1 * 47000, cytochrome component, + 1 * 25000, function unclear, SDS-PAGE
trimer
A0A0B6VQG4; A0A0B6VN56; A0A0B6VKP6;
a small subunit, a large subunit, and a cytochrome c subunit
trimer
-
a small subunit, a large subunit, and a cytochrome c subunit
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
pH STABILITY
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
GENERAL STABILITY
ORGANISM
UNIPROT
LITERATURE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
expressed in Gluconobacter japonicas strain NBRC3271
A0A0B6VQG4; A0A0B6VN56; A0A0B6VKP6;
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
APPLICATION
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
LINKS TO OTHER DATABASES (specific for EC-Number 1.1.99.4)
html completed
Use of this online version of BRENDA is free but requires a license. See terms of use.
Information
