Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Disease on EC 1.1.99.2 - L-2-hydroxyglutarate dehydrogenase

Please use the Disease Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Brain Diseases
A novel compound heterozygous mutation in a Chinese boy with L-2-hydroxyglutaric aciduria: a case study.
Brain Neoplasms
L-2-hydroxyglutaric aciduria and brain tumors in children with mutations in the L2HGDH gene: neuroimaging findings.
Mutational analysis of D2HGDH and L2HGDH in brain tumours without IDH1 or IDH2 mutations.
Carcinoma
Biochemical and Epigenetic Insights into L-2-Hydroxyglutarate, a Potential Therapeutic Target in Renal Cancer.
Epigenetic dysregulation by aberrant metabolism in renal cell carcinoma can be reversed with Ascorbic acid.
Carcinoma, Renal Cell
Biochemical and Epigenetic Insights into L-2-Hydroxyglutarate, a Potential Therapeutic Target in Renal Cancer.
Epigenetic dysregulation by aberrant metabolism in renal cell carcinoma can be reversed with Ascorbic acid.
Drug Resistant Epilepsy
White matter abnormalities in an adult patient with l-2-hydroxyglutaric aciduria.
Glioblastoma
LCN2-interacting proteins and their expression patterns in brain tumors.
Screen for IDH1, IDH2, IDH3, D2HGDH and L2HGDH mutations in glioblastoma.
Intellectual Disability
White matter abnormalities in an adult patient with l-2-hydroxyglutaric aciduria.
Kidney Neoplasms
Teleological Role of L-2-Hydroxyglutarate Dehydrogenase in the Kidney.
l-2-hydroxyglutarate dehydrogenase deficiency
Adult manifestation of L-2-hydroxyglutarate dehydrogenase deficiency by a novel mutation.
Familial hyperlysinaemia due to L-lysine alpha-ketoglutarate reductase deficiency: results of attempted treatment.
L2hgdh Deficiency Accumulates l-2-Hydroxyglutarate with Progressive Leukoencephalopathy and Neurodegeneration.
Leukoencephalopathies
L2hgdh Deficiency Accumulates l-2-Hydroxyglutarate with Progressive Leukoencephalopathy and Neurodegeneration.
Metabolite proofreading, a neglected aspect of intermediary metabolism.
Neoplasms
Another small molecule in the oncometabolite mix: L-2-Hydroxyglutarate in kidney cancer.
Biochemical and Epigenetic Insights into L-2-Hydroxyglutarate, a Potential Therapeutic Target in Renal Cancer.
L-2-Hydroxyglutarate: an epigenetic modifier and putative oncometabolite in renal cancer.
Screen for IDH1, IDH2, IDH3, D2HGDH and L2HGDH mutations in glioblastoma.
Teleological Role of L-2-Hydroxyglutarate Dehydrogenase in the Kidney.
Neuroinflammatory Diseases
L2hgdh Deficiency Accumulates l-2-Hydroxyglutarate with Progressive Leukoencephalopathy and Neurodegeneration.
Starvation
An L-2-hydroxyglutarate biosensor based on specific transcriptional regulator LhgR.