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Information on EC 1.1.5.12 - D-lactate dehydrogenase (quinone)

for references in articles please use BRENDA:EC1.1.5.12

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IUBMB Comments

The enzyme is an FAD-dependent peripheral membrane dehydrogenase that participates in respiration. Electrons derived from D-lactate oxidation are transferred to the membrane soluble quinone pool.

The enzyme appears in viruses and cellular organisms

Synonyms
quinone-dependent d-lactate dehydrogenase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(R)-lactate + a quinone = pyruvate + a quinol
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
MetaCyc
2-chloroacrylate degradation I, D-lactate to cytochrome bo oxidase electron transfer, methylglyoxal degradation I
Highest Expressing Human Cell Lines
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