Information on EC 1.1.4.2 - vitamin-K-epoxide reductase (warfarin-insensitive)

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Old data from external sources may still be available.
Please check here for current data: EC 1.17.4.5

EC Tree 1 Oxidoreductases 1.1 Acting on the CH-OH group of donors 1.1.4 With a disulfide as acceptor 1.1.4.2 vitamin-K-epoxide reductase (warfarin-insensitive)

IUBMB Comments

In the reverse reaction, vitamin K 2,3-epoxide is reduced to 3-hydroxy- (and 2-hydroxy-) vitamin K by 1,4-dithiothreitol, which is oxidized to a disulfide. Not inhibited by warfarin [cf. EC 1.1.4.1 vitamin-K-epoxide reductase (warfarin-sensitive)].

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

Synechococcus sp. JA-2-3B\''a(2-13)

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.