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Information on EC 1.1.3.44 - 6'''-hydroxyneomycin C oxidase

for references in articles please use BRENDA:EC1.1.3.44

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IUBMB Comments

Contains FAD. Involved in the biosynthetic pathway of aminoglycoside antibiotics of the neomycin family. Works in combination with EC 2.6.1.95, neomycin C transaminase, to replace the 6′′′-hydroxy group of 6′′′-hydroxyneomycin C with an amino group. Also catalyses EC 1.1.3.43, paromamine 6'-oxidase.

The enzyme appears in viruses and cellular organisms

Synonyms
neo-11, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
6'''-deamino-6'''-hydroxyneomycin C + O2 = 6'''-deamino-6'''-oxoneomycin C + H2O2
show the reaction diagram
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