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Information on EC - nucleoside oxidase (H2O2-forming)

for references in articles please use BRENDA:EC1.1.3.39
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IUBMB Comments
A heme-containing flavoprotein (FAD). Other purine and pyrimidine nucleosides (as well as 2'-deoxyribonucleosides and arabinosides) are substrates, but ribose and nucleotides are not substrates. The overall reaction takes place in two separate steps, with the 5'-dehydro nucleoside being released from the enzyme to serve as substrate for the second reaction. This enzyme differs from EC, nucleoside oxidase, as it produces hydrogen peroxide rather than water.
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The expected taxonomic range for this enzyme is: Elizabethkingia meningoseptica
adenosine + 2 O2 + H2O = 9-riburonosyladenine + 2 H2O2
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adenosine + O2 = 5'-dehydroadenosine + H2O2
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