Disease on EC 1.1.2.2 - mannitol dehydrogenase (cytochrome)
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Adenocarcinoma
Metadherin confers chemoresistance of cervical cancer cells by inducing autophagy and activating ERK/NF-?B pathway.
Adenocarcinoma
MiR-1297 suppresses pancreatic cancer cell proliferation and metastasis by targeting MTDH.
Adenocarcinoma
MTDH and EphA7 are markers for metastasis and poor prognosis of gallbladder adenocarcinoma.
Adenoma
Downregulation of miR-375 in aldosterone-producing adenomas promotes tumour cell growth via MTDH.
Breast Neoplasms
A novel metadherin?7 splice variant enhances triple negative breast cancer aggressiveness by modulating mitochondrial function via NF?B-SIRT3 axis.
Breast Neoplasms
A polysaccharide from Huaier induced apoptosis in MCF-7 breast cancer cells via down-regulation of MTDH protein.
Breast Neoplasms
A Preliminary Study on Metadherin as a Potential Marker for Progression of Diffuse Large B Cell Lymphoma.
Breast Neoplasms
AMPK inhibits MTDH expression via GSK3? and SIRT1 activation: potential role in triple negative breast cancer cell proliferation.
Breast Neoplasms
Association of MTDH immunohistochemical expression with metastasis and prognosis in female reproduction malignancies: a systematic review and meta-analysis.
Breast Neoplasms
Berberine Inhibits Proliferative Ability of Breast Cancer Cells by Reducing Metadherin.
Breast Neoplasms
Efficient and tumor-specific knockdown of MTDH gene attenuates paclitaxel resistance of breast cancer cells both in vivo and in vitro.
Breast Neoplasms
Elevated expression of MTDH predicts better prognosis of locally advanced HER-2 positive breast cancer patients receiving neoadjuvant chemotherapy plus trastuzumab.
Breast Neoplasms
Epigenetic Activation of TWIST1 by MTDH Promotes Cancer Stem-like Cell Traits in Breast Cancer.
Breast Neoplasms
Establishment and Characterization of MTDH Knockdown by Artificial MicroRNA Interference - Functions as a Potential Tumor Suppressor in Breast Cancer.
Breast Neoplasms
Expression of MTDH and IL-10 Is an Independent Predictor of Worse Prognosis in ER-Negative or PR-Negative Breast Cancer Patients.
Breast Neoplasms
Gene expression profiling of the 8q22-24 position in human breast cancer: TSPYL5, MTDH, ATAD2 and CCNE2 genes are implicated in oncogenesis, while WISP1 and EXT1 genes may predict a risk of metastasis.
Breast Neoplasms
Identification of Staphylococcal nuclease domain containing 1 (SND1) as a Metadherin-interacting protein with metastasis-promoting functions.
Breast Neoplasms
Immunohistochemical analysis of Metadherin in proliferative and cancerous breast tissue.
Breast Neoplasms
Knockdown of long noncoding RNA TP73-AS1 suppresses the malignant progression of breast cancer cells in vitro through targeting miRNA-125a-3p/metadherin axis.
Breast Neoplasms
Knockdown of MTDH sensitizes endometrial cancer cells to cell death induction by death receptor ligand TRAIL and HDAC inhibitor LBH589 co-treatment.
Breast Neoplasms
Lobaplatin inhibits breast cancer progression, cell proliferation while it induces cell apoptosis by downregulating MTDH expression.
Breast Neoplasms
Metadherin enhances the invasiveness of breast cancer cells by inducing epithelial to mesenchymal transition.
Breast Neoplasms
MicroRNA-30a suppresses breast tumor growth and metastasis by targeting metadherin.
Breast Neoplasms
MicroRNA-876 is sponged by long noncoding RNA LINC00707 and directly targets metadherin to inhibit breast cancer malignancy.
Breast Neoplasms
MiR-153 inhibits epithelial-mesenchymal transition by targeting metadherin in human breast cancer.
Breast Neoplasms
MiR-26a inhibits proliferation and migration of breast cancer through repression of MCL-1.
Breast Neoplasms
Molecular Modification of Metadherin/MTDH Impacts the Sensitivity of Breast Cancer to Doxorubicin.
Breast Neoplasms
MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor-prognosis breast cancer.
Breast Neoplasms
MTDH mediates estrogen-independent growth and tamoxifen resistance by down-regulating PTEN in MCF-7 breast cancer cells.
Breast Neoplasms
MTDH mediates trastuzumab resistance in HER2 positive breast cancer by decreasing PTEN expression through an NF?B-dependent pathway.
Breast Neoplasms
MTDH-SND1 interaction is crucial for expansion and activity of tumor-initiating cells in diverse oncogene- and carcinogen-induced mammary tumors.
Breast Neoplasms
Overexpression of metadherin/MTDH is associated with an aggressive phenotype and a poor prognosis in invasive breast cancer.
Breast Neoplasms
Pathologically Decreased MiR-26a Antagonizes Apoptosis and Facilitates Carcinogenesis by targeting MTDH and EZH2 in Breast Cancer.
Breast Neoplasms
Phenethyl Isothiocyanate Suppresses Stemness in the Chemo- and Radio-Resistant Triple-Negative Breast Cancer Cell Line MDA-MB-231/IR Via Downregulation of Metadherin.
Breast Neoplasms
Post-trimodality expression levels of metadherin (MTDH) as a prognostic biomarker for esophageal adenocarcinoma patients.
Breast Neoplasms
Re-expression of microRNA-375 reverses both tamoxifen resistance and accompanying EMT-like properties in breast cancer.
Breast Neoplasms
Structural insights into the tumor-promoting function of the MTDH-SND1 complex.
Breast Neoplasms
SU6668 suppresses proliferation of triple negative breast cancer cells through down-regulating MTDH expression.
Breast Neoplasms
The Antitumor Effect of Metformin Is Mediated by miR-26a in Breast Cancer.
Breast Neoplasms
The FBXW7 tumor suppressor inhibits breast cancer proliferation and promotes apoptosis by targeting MTDH for degradation.
Breast Neoplasms
The MTDH (-470G>A) polymorphism is associated with ovarian cancer susceptibility.
Breast Neoplasms
The Oncogene Metadherin Modulates the Apoptotic Pathway Based on the Tumor Necrosis Factor Superfamily Member TRAIL (Tumor Necrosis Factor-related Apoptosis-inducing Ligand) in Breast Cancer.
Breast Neoplasms
Ultrasound-Targeted Microbubble Destruction (UTMD) Combined with Liposome Increases the Effectiveness of Suppressing Proliferation, Migration, Invasion, and Epithelial- Mesenchymal Transition (EMT) via Targeting Metadherin (MTDH) by ShRNA.
Breast Neoplasms
[Expression and clinical significance of MTDH and VEGF in triple-negative breast cancer].
Breast Neoplasms, Male
Oncogene amplification in male breast cancer: analysis by multiplex ligation-dependent probe amplification.
Carcinogenesis
Gene expression profiling of the 8q22-24 position in human breast cancer: TSPYL5, MTDH, ATAD2 and CCNE2 genes are implicated in oncogenesis, while WISP1 and EXT1 genes may predict a risk of metastasis.
Carcinogenesis
Immunohistochemical analysis of Metadherin in proliferative and cancerous breast tissue.
Carcinogenesis
Metadherin Expression is Associated with Extrathyroidal Extension in Papillary Thyroid Cancer Patients.
Carcinogenesis
Metadherin/Astrocyte elevated gene-1 positively regulates the stability and function of forkhead box M1 during tumorigenesis.
Carcinogenesis
Metadherin: An emerging key regulator of the malignant progression of multiple cancers.
Carcinogenesis
MTDH and EphA7 are markers for metastasis and poor prognosis of gallbladder adenocarcinoma.
Carcinogenesis
MTDH-SND1 interaction is crucial for expansion and activity of tumor-initiating cells in diverse oncogene- and carcinogen-induced mammary tumors.
Carcinogenesis
Pathologically Decreased MiR-26a Antagonizes Apoptosis and Facilitates Carcinogenesis by targeting MTDH and EZH2 in Breast Cancer.
Carcinogenesis
The FBXW7 tumor suppressor inhibits breast cancer proliferation and promotes apoptosis by targeting MTDH for degradation.
Carcinoma
Apoptosis of human non-small-cell lung cancer A549 cells triggered by evodiamine through MTDH-dependent signaling pathway.
Carcinoma
Dual-strand tumor-suppressor microRNA-145 (miR-145-5p and miR-145-3p) coordinately targeted MTDH in lung squamous cell carcinoma.
Carcinoma
Immunohistochemical analysis of Metadherin in proliferative and cancerous breast tissue.
Carcinoma
Increased expression of metadherin protein predicts worse disease-free and overall survival in laryngeal squamous cell carcinoma.
Carcinoma
Metadherin exon 11 skipping variant enhances metastatic spread of ovarian cancer.
Carcinoma
Metadherin is required for the proliferation, migration, and invasion of esophageal squamous cell carcinoma and its meta-analysis.
Carcinoma
MicroRNA?98/PTEN/AKT pathway inhibits cell proliferation and malignant progression of hypopharyngeal carcinoma by MTDH.
Carcinoma
MiR-98 inhibits malignant progression via targeting MTDH in squamous cell carcinoma of the head and neck.
Carcinoma
MTDH in macrophages promotes the vasculogenic mimicry via VEGFA-165/Flt-1 signaling pathway in head and neck squamous cell carcinoma.
Carcinoma
MTDH promotes metastasis of clear cell renal cell carcinoma by activating SND1-mediated ERK signaling and epithelial-mesenchymal transition.
Carcinoma
[Expression and clinical significance of MTDH, HIF-1? and TKTL1 in laryngeal carcinoma].
Carcinoma
[Expression and significance of MTDH and MMP-9 in laryngeal squamous cell carcinoma].
Carcinoma, Hepatocellular
A Preliminary Study on Metadherin as a Potential Marker for Progression of Diffuse Large B Cell Lymphoma.
Carcinoma, Hepatocellular
CPEB3-mediated MTDH mRNA translational suppression restrains hepatocellular carcinoma progression.
Carcinoma, Hepatocellular
Knockdown of MTDH sensitizes endometrial cancer cells to cell death induction by death receptor ligand TRAIL and HDAC inhibitor LBH589 co-treatment.
Carcinoma, Hepatocellular
Lentiviral-Mediated Short Hairpin RNA Knockdown of MTDH Inhibits Cell Growth and Induces Apoptosis by Regulating the PTEN/AKT Pathway in Hepatocellular Carcinoma.
Carcinoma, Hepatocellular
Metadherin-PRMT5 complex enhances the metastasis of hepatocellular carcinoma through the WNT-?-catenin signaling pathway.
Carcinoma, Hepatocellular
miR-217 suppresses proliferation, migration, and invasion promoting apoptosis via targeting MTDH in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Prognostic significance of metadherin overexpression in hepatitis B virus-related hepatocellular carcinoma.
Carcinoma, Hepatocellular
Repression of metadherin inhibits biological behavior of prostate cancer cells and enhances their sensitivity to cisplatin.
Carcinoma, Intraductal, Noninfiltrating
Immunohistochemical analysis of Metadherin in proliferative and cancerous breast tissue.
Carcinoma, Intraductal, Noninfiltrating
Molecular differences between ductal carcinoma in situ and adjacent invasive breast carcinoma: A multiplex ligation-dependent probe amplification study.
Carcinoma, Non-Small-Cell Lung
Apoptosis of human non-small-cell lung cancer A549 cells triggered by evodiamine through MTDH-dependent signaling pathway.
Carcinoma, Non-Small-Cell Lung
Long noncoding RNA SNHG1 promotes non-small cell lung cancer progression by up-regulating MTDH via sponging miR-145-5p.
Carcinoma, Non-Small-Cell Lung
MicroRNA-584 inhibits cell proliferation and invasion in non-small cell lung cancer by directly targeting MTDH.
Carcinoma, Non-Small-Cell Lung
miR-145 and miR-497 suppress TGF-?-induced epithelial-mesenchymal transition of non-small cell lung cancer by targeting MTDH.
Carcinoma, Renal Cell
MTDH promotes metastasis of clear cell renal cell carcinoma by activating SND1-mediated ERK signaling and epithelial-mesenchymal transition.
Carcinoma, Squamous Cell
Dual-strand tumor-suppressor microRNA-145 (miR-145-5p and miR-145-3p) coordinately targeted MTDH in lung squamous cell carcinoma.
Carcinoma, Squamous Cell
Metadherin confers chemoresistance of cervical cancer cells by inducing autophagy and activating ERK/NF-?B pathway.
Carcinoma, Squamous Cell
Metadherin is required for the proliferation, migration, and invasion of esophageal squamous cell carcinoma and its meta-analysis.
Carcinoma, Squamous Cell
MiR-98 inhibits malignant progression via targeting MTDH in squamous cell carcinoma of the head and neck.
Carcinoma, Squamous Cell
MTDH in macrophages promotes the vasculogenic mimicry via VEGFA-165/Flt-1 signaling pathway in head and neck squamous cell carcinoma.
Carcinoma, Squamous Cell
[Expression and clinical significance of MTDH, HIF-1? and TKTL1 in laryngeal carcinoma].
Cluster Headache
Implications for the migraine SNP rs1835740 in a Swedish cluster headache population.
Colonic Neoplasms
Overexpression of miR-22 reverses paclitaxel-induced chemoresistance through activation of PTEN signaling in p53-mutated colon cancer cells.
Colorectal Neoplasms
Effect of modification of MTDH gene expression on colorectal cancer aggressiveness.
Colorectal Neoplasms
Knockdown of metadherin inhibits cell proliferation and migration in colorectal cancer.
Colorectal Neoplasms
MicroRNA-1271 suppresses the proliferation and invasion of colorectal cancer cells by regulating metadherin/Wnt signaling.
Colorectal Neoplasms
microRNA-877 inhibits malignant progression of colorectal cancer by directly targeting MTDH and regulating the PTEN/Akt pathway.
Colorectal Neoplasms
MiR-182-5p inhibited proliferation and metastasis of colorectal cancer by targeting MTDH.
Colorectal Neoplasms
MTDH and MAP3K1 are direct targets of apoptosis-regulating miRNAs in colorectal carcinoma.
Colorectal Neoplasms
RARRES3 suppressed metastasis through suppression of MTDH to regulate epithelial-mesenchymal transition in colorectal cancer.
Endometrial Neoplasms
Cytoplasmic Metadherin (MTDH) Provides Survival Advantage under Conditions of Stress by Acting as RNA-binding Protein.
Endometrial Neoplasms
Knockdown of MTDH sensitizes endometrial cancer cells to cell death induction by death receptor ligand TRAIL and HDAC inhibitor LBH589 co-treatment.
Endometrial Neoplasms
Transcriptional Repression of Raf Kinase Inhibitory Protein Gene by Metadherin during Cancer Progression.
Esophageal Squamous Cell Carcinoma
Metadherin is required for the proliferation, migration, and invasion of esophageal squamous cell carcinoma and its meta-analysis.
Fanconi Anemia
MTDH/AEG-1 downregulation using pristimerin-loaded nanoparticles inhibits Fanconi anemia proteins and increases sensitivity to platinum-based chemotherapy.
Fibroadenoma
[Expression and clinical significance of MTDH and VEGF in triple-negative breast cancer].
Glioblastoma
Post-trimodality expression levels of metadherin (MTDH) as a prognostic biomarker for esophageal adenocarcinoma patients.
Glioma
A Preliminary Study on Metadherin as a Potential Marker for Progression of Diffuse Large B Cell Lymphoma.
Glioma
microRNA-1471 suppresses glioma cell growth and invasion by repressing metadherin expression.
Glioma
MicroRNA-202 inhibits cell proliferation, migration and invasion of glioma by directly targeting metadherin.
Glioma
MicroRNA-379 inhibits cell proliferation and invasion in glioma via targeting metadherin and regulating PTEN/AKT pathway.
Glioma
MicroRNA?216b inhibits cell proliferation and invasion in glioma by directly targeting metadherin.
Glioma
MiR-302c-3p suppresses invasion and proliferation of glioma cells via down-regulating metadherin (MTDH) expression.
Hepatitis B
Prognostic significance of metadherin overexpression in hepatitis B virus-related hepatocellular carcinoma.
Hepatitis B, Chronic
Prognostic significance of metadherin overexpression in hepatitis B virus-related hepatocellular carcinoma.
Infertility, Male
Genetic Deficiency of Mtdh Gene in Mice Causes Male Infertility via Impaired Spermatogenesis and Alterations in the Expression of Small Non-coding RNAs.
Klatskin Tumor
Metadherin overexpression in perihilar cholangiocarcinoma is associated with lymph node metastasis and poor prognosis.
Leukemia, Lymphocytic, Chronic, B-Cell
Metadherin contributes to the pathogenesis of chronic lymphocytic leukemia partially through Wnt/?-catenin pathway.
Liver Neoplasms
Overexpression of microRNA-30a-5p inhibits liver cancer cell proliferation and induces apoptosis by targeting MTDH/PTEN/AKT pathway.
Lung Neoplasms
Apoptosis of human non-small-cell lung cancer A549 cells triggered by evodiamine through MTDH-dependent signaling pathway.
Lung Neoplasms
FHIT suppresses epithelial-mesenchymal transition (EMT) and metastasis in lung cancer through modulation of microRNAs.
Lung Neoplasms
Huaier Granule extract inhibit the proliferation and metastasis of lung cancer cells through down-regulation of MTDH, JAK2/STAT3 and MAPK signaling pathways.
Lung Neoplasms
Long noncoding RNA SNHG1 promotes non-small cell lung cancer progression by up-regulating MTDH via sponging miR-145-5p.
Lung Neoplasms
MicroRNA-584 inhibits cell proliferation and invasion in non-small cell lung cancer by directly targeting MTDH.
Lung Neoplasms
miR-145 and miR-497 suppress TGF-?-induced epithelial-mesenchymal transition of non-small cell lung cancer by targeting MTDH.
Lung Neoplasms
Repression of metadherin inhibits biological behavior of prostate cancer cells and enhances their sensitivity to cisplatin.
Lung Neoplasms
Therapeutic Targeting of Metadherin Suppresses Colorectal and Lung Cancer Progression and Metastasis.
Lymphatic Metastasis
Association of MTDH immunohistochemical expression with metastasis and prognosis in female reproduction malignancies: a systematic review and meta-analysis.
Lymphatic Metastasis
Correlation between down-expression of miR-431 and clinicopathological significance in HCC tissues.
Lymphatic Metastasis
Elevated expression of MTDH predicts better prognosis of locally advanced HER-2 positive breast cancer patients receiving neoadjuvant chemotherapy plus trastuzumab.
Lymphatic Metastasis
Increased expression of metadherin protein predicts worse disease-free and overall survival in laryngeal squamous cell carcinoma.
Lymphatic Metastasis
Metadherin Expression is Associated with Extrathyroidal Extension in Papillary Thyroid Cancer Patients.
Lymphatic Metastasis
Metadherin is required for the proliferation, migration, and invasion of esophageal squamous cell carcinoma and its meta-analysis.
Lymphatic Metastasis
Metadherin overexpression in perihilar cholangiocarcinoma is associated with lymph node metastasis and poor prognosis.
Lymphatic Metastasis
Metadherin regulates actin cytoskeletal remodeling and enhances human gastric cancer metastasis via epithelial-mesenchymal transition.
Lymphatic Metastasis
[Expression and clinical significance of MTDH and VEGF in triple-negative breast cancer].
Lymphoma
Metadherin interference inhibits proliferation and enhances chemo-sensitivity to doxorubicin in diffuse large B cell lymphoma.
Lymphoma, B-Cell
A Preliminary Study on Metadherin as a Potential Marker for Progression of Diffuse Large B Cell Lymphoma.
Lymphoma, B-Cell
Metadherin interference inhibits proliferation and enhances chemo-sensitivity to doxorubicin in diffuse large B cell lymphoma.
Lymphoma, Large B-Cell, Diffuse
A Preliminary Study on Metadherin as a Potential Marker for Progression of Diffuse Large B Cell Lymphoma.
Lymphoma, Large B-Cell, Diffuse
Metadherin interference inhibits proliferation and enhances chemo-sensitivity to doxorubicin in diffuse large B cell lymphoma.
Melanoma
A Preliminary Study on Metadherin as a Potential Marker for Progression of Diffuse Large B Cell Lymphoma.
Melanoma
MicroRNA?675 inhibits cell proliferation and invasion in melanoma by directly targeting metadherin.
Melanoma
miR-let-7b and miR-let-7c suppress tumourigenesis of human mucosal melanoma and enhance the sensitivity to chemotherapy.
Melanoma
Post-trimodality expression levels of metadherin (MTDH) as a prognostic biomarker for esophageal adenocarcinoma patients.
Melanoma
[Expression and prognostic value of MTDH, Bcl-2 and E-cadherin in sinonasal malignant mucosal melanoma].
Migraine Disorders
Implications for the migraine SNP rs1835740 in a Swedish cluster headache population.
Multiple Myeloma
MTDH is an oncogene in multiple myeloma, which is suppressed by Bortezomib treatment.
Neoplasm Metastasis
Association of MTDH immunohistochemical expression with metastasis and prognosis in female reproduction malignancies: a systematic review and meta-analysis.
Neoplasm Metastasis
Correlation between down-expression of miR-431 and clinicopathological significance in HCC tissues.
Neoplasm Metastasis
CPEB3-mediated MTDH mRNA translational suppression restrains hepatocellular carcinoma progression.
Neoplasm Metastasis
Elevated expression of MTDH predicts better prognosis of locally advanced HER-2 positive breast cancer patients receiving neoadjuvant chemotherapy plus trastuzumab.
Neoplasm Metastasis
Epigenetic Activation of TWIST1 by MTDH Promotes Cancer Stem-like Cell Traits in Breast Cancer.
Neoplasm Metastasis
Expression of MTDH and IL-10 Is an Independent Predictor of Worse Prognosis in ER-Negative or PR-Negative Breast Cancer Patients.
Neoplasm Metastasis
FHIT suppresses epithelial-mesenchymal transition (EMT) and metastasis in lung cancer through modulation of microRNAs.
Neoplasm Metastasis
Gene expression profiling of the 8q22-24 position in human breast cancer: TSPYL5, MTDH, ATAD2 and CCNE2 genes are implicated in oncogenesis, while WISP1 and EXT1 genes may predict a risk of metastasis.
Neoplasm Metastasis
Genetic ablation of metadherin inhibits autochthonous prostate cancer progression and metastasis.
Neoplasm Metastasis
Genomic evolution from primary breast carcinoma to distant metastasis: Few copy number changes of breast cancer related genes.
Neoplasm Metastasis
Huaier Granule extract inhibit the proliferation and metastasis of lung cancer cells through down-regulation of MTDH, JAK2/STAT3 and MAPK signaling pathways.
Neoplasm Metastasis
Hypoxia promotes migration/invasion and glycolysis in head and neck squamous cell carcinoma via an HIF-1?-MTDH loop.
Neoplasm Metastasis
Identification of Staphylococcal nuclease domain containing 1 (SND1) as a Metadherin-interacting protein with metastasis-promoting functions.
Neoplasm Metastasis
Increased expression of metadherin protein predicts worse disease-free and overall survival in laryngeal squamous cell carcinoma.
Neoplasm Metastasis
Metadherin exon 11 skipping variant enhances metastatic spread of ovarian cancer.
Neoplasm Metastasis
Metadherin expression and lung relapse in patients with colorectal carcinoma.
Neoplasm Metastasis
Metadherin Expression is Associated with Extrathyroidal Extension in Papillary Thyroid Cancer Patients.
Neoplasm Metastasis
Metadherin in prostate, bladder, and kidney cancer: A systematic review.
Neoplasm Metastasis
Metadherin is required for the proliferation, migration, and invasion of esophageal squamous cell carcinoma and its meta-analysis.
Neoplasm Metastasis
Metadherin overexpression in perihilar cholangiocarcinoma is associated with lymph node metastasis and poor prognosis.
Neoplasm Metastasis
Metadherin Promotes Malignant Phenotypes And Induces Beta-Catenin Nuclear Translocation And Epithelial-Mesenchymal Transition In Gastric Cancer.
Neoplasm Metastasis
Metadherin promotes metastasis by supporting putative cancer stem cell properties and epithelial plasticity in pancreatic cancer.
Neoplasm Metastasis
Metadherin regulates actin cytoskeletal remodeling and enhances human gastric cancer metastasis via epithelial-mesenchymal transition.
Neoplasm Metastasis
Metadherin regulates metastasis of squamous cell carcinoma of the head and neck via AKT signalling pathway-mediated epithelial- mesenchymal transition.
Neoplasm Metastasis
Metadherin regulates proliferation and metastasis via actin cytoskeletal remodelling in non-small cell lung cancer.
Neoplasm Metastasis
Metadherin Regulation of Vascular Endothelial Growth Factor Expression Is Dependent Upon the PI3K/Akt Pathway in Squamous Cell Carcinoma of the Head and Neck.
Neoplasm Metastasis
Metadherin-PRMT5 complex enhances the metastasis of hepatocellular carcinoma through the WNT-?-catenin signaling pathway.
Neoplasm Metastasis
Metadherin: An emerging key regulator of the malignant progression of multiple cancers.
Neoplasm Metastasis
MicroRNA-154 inhibits the growth and metastasis of gastric cancer cells by directly targeting MTDH.
Neoplasm Metastasis
MicroRNA-202 inhibits cell proliferation, migration and invasion of glioma by directly targeting metadherin.
Neoplasm Metastasis
microRNA-22 acts as a metastasis suppressor by targeting metadherin in gastric cancer.
Neoplasm Metastasis
MicroRNA-30a suppresses breast tumor growth and metastasis by targeting metadherin.
Neoplasm Metastasis
MicroRNA-320a inhibits breast cancer metastasis by targeting metadherin.
Neoplasm Metastasis
MicroRNA-618 Directly Targets Metadherin mRNA To Suppress The Malignant Phenotype Of Osteosarcoma Cells By Reducing PTEN-AKT Pathway Output.
Neoplasm Metastasis
MiR-1297 suppresses pancreatic cancer cell proliferation and metastasis by targeting MTDH.
Neoplasm Metastasis
miR-145 inhibits tumor growth and metastasis by targeting metadherin in high-grade serous ovarian carcinoma.
Neoplasm Metastasis
MiR-182-5p inhibited proliferation and metastasis of colorectal cancer by targeting MTDH.
Neoplasm Metastasis
miR-26a suppresses tumour proliferation and metastasis by targeting metadherin in triple negative breast cancer.
Neoplasm Metastasis
miR-let-7b and miR-let-7c suppress tumourigenesis of human mucosal melanoma and enhance the sensitivity to chemotherapy.
Neoplasm Metastasis
miR?3664?5P suppresses the proliferation and metastasis of gastric cancer by attenuating the NF??B signaling pathway through targeting MTDH.
Neoplasm Metastasis
MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor-prognosis breast cancer.
Neoplasm Metastasis
MTDH and EphA7 are markers for metastasis and poor prognosis of gallbladder adenocarcinoma.
Neoplasm Metastasis
MTDH in macrophages promotes the vasculogenic mimicry via VEGFA-165/Flt-1 signaling pathway in head and neck squamous cell carcinoma.
Neoplasm Metastasis
MTDH promotes metastasis of clear cell renal cell carcinoma by activating SND1-mediated ERK signaling and epithelial-mesenchymal transition.
Neoplasm Metastasis
Overexpression of metadherin mediates metastasis of osteosarcoma by regulating epithelial-mesenchymal transition.
Neoplasm Metastasis
RARRES3 suppressed metastasis through suppression of MTDH to regulate epithelial-mesenchymal transition in colorectal cancer.
Neoplasm Metastasis
Re-expression of microRNA-375 reverses both tamoxifen resistance and accompanying EMT-like properties in breast cancer.
Neoplasm Metastasis
Silencing the expression of MTDH increases the radiation sensitivity of SKOV3 ovarian cancer cells and reduces their proliferation and metastasis.
Neoplasm Metastasis
Synergistic Effect of Cold Atmospheric Plasma and Drug Loaded Core-shell Nanoparticles on Inhibiting Breast Cancer Cell Growth.
Neoplasm Metastasis
The essential role of MTDH in the progression of HCC: a study with immunohistochemistry, TCGA, meta-analysis and in vitro investigation.
Neoplasm Metastasis
The targeting of MTDH by miR?145?5p or miR?145?3p is associated with prognosis and regulates the growth and metastasis of prostate cancer cells.
Neoplasm Metastasis
Therapeutic Targeting of Metadherin Suppresses Colorectal and Lung Cancer Progression and Metastasis.
Neoplasm Metastasis
Upregulated MiR-1269 in hepatocellular carcinoma and its clinical significance.
Neoplasm Metastasis
[Expression and clinical significance of MTDH and VEGF in triple-negative breast cancer].
Neoplasm Metastasis
[Expression and clinical significance of MTDH, HIF-1? and TKTL1 in laryngeal carcinoma].
Neoplasm Metastasis
[Expression and significance of MTDH and MMP-9 in laryngeal squamous cell carcinoma].
Neoplasms
A polysaccharide from Trametes robiniophila Murrill induces apoptosis through intrinsic mitochondrial pathway in human osteosarcoma (U-2 OS) cells.
Neoplasms
A Preliminary Study on Metadherin as a Potential Marker for Progression of Diffuse Large B Cell Lymphoma.
Neoplasms
Apoptosis of human non-small-cell lung cancer A549 cells triggered by evodiamine through MTDH-dependent signaling pathway.
Neoplasms
Association of MTDH immunohistochemical expression with metastasis and prognosis in female reproduction malignancies: a systematic review and meta-analysis.
Neoplasms
Cytoplasmic Metadherin (MTDH) Provides Survival Advantage under Conditions of Stress by Acting as RNA-binding Protein.
Neoplasms
Downregulation of miR-375 in aldosterone-producing adenomas promotes tumour cell growth via MTDH.
Neoplasms
Effect of modification of MTDH gene expression on colorectal cancer aggressiveness.
Neoplasms
Efficient and tumor-specific knockdown of MTDH gene attenuates paclitaxel resistance of breast cancer cells both in vivo and in vitro.
Neoplasms
Elevated expression of MTDH predicts better prognosis of locally advanced HER-2 positive breast cancer patients receiving neoadjuvant chemotherapy plus trastuzumab.
Neoplasms
Epigenetic Activation of TWIST1 by MTDH Promotes Cancer Stem-like Cell Traits in Breast Cancer.
Neoplasms
Establishment and Characterization of MTDH Knockdown by Artificial MicroRNA Interference - Functions as a Potential Tumor Suppressor in Breast Cancer.
Neoplasms
Expression of MTDH and IL-10 Is an Independent Predictor of Worse Prognosis in ER-Negative or PR-Negative Breast Cancer Patients.
Neoplasms
FHIT suppresses epithelial-mesenchymal transition (EMT) and metastasis in lung cancer through modulation of microRNAs.
Neoplasms
Genetic ablation of metadherin inhibits autochthonous prostate cancer progression and metastasis.
Neoplasms
Genomic evolution from primary breast carcinoma to distant metastasis: Few copy number changes of breast cancer related genes.
Neoplasms
Hypoxia promotes migration/invasion and glycolysis in head and neck squamous cell carcinoma via an HIF-1?-MTDH loop.
Neoplasms
Immunohistochemical analysis of Metadherin in proliferative and cancerous breast tissue.
Neoplasms
Increased expression of metadherin protein predicts worse disease-free and overall survival in laryngeal squamous cell carcinoma.
Neoplasms
Increased HSF1 Promotes Infiltration and Metastasis in Cervical Cancer via Enhancing MTDH-VEGF-C Expression.
Neoplasms
Knockdown of metadherin inhibits cell proliferation and migration in colorectal cancer.
Neoplasms
Lentiviral-Mediated Short Hairpin RNA Knockdown of MTDH Inhibits Cell Growth and Induces Apoptosis by Regulating the PTEN/AKT Pathway in Hepatocellular Carcinoma.
Neoplasms
Metadherin Expression is Associated with Extrathyroidal Extension in Papillary Thyroid Cancer Patients.
Neoplasms
Metadherin is a novel prognostic marker for bladder cancer progression and overall patient survival.
Neoplasms
Metadherin Is a Prognostic Apoptosis Modulator in Mesothelioma Induced via NF-?B-Mediated Signaling.
Neoplasms
Metadherin overexpression in perihilar cholangiocarcinoma is associated with lymph node metastasis and poor prognosis.
Neoplasms
Metadherin Promotes Malignant Phenotypes And Induces Beta-Catenin Nuclear Translocation And Epithelial-Mesenchymal Transition In Gastric Cancer.
Neoplasms
Metadherin promotes metastasis by supporting putative cancer stem cell properties and epithelial plasticity in pancreatic cancer.
Neoplasms
Metadherin regulates actin cytoskeletal remodeling and enhances human gastric cancer metastasis via epithelial-mesenchymal transition.
Neoplasms
Metadherin/Astrocyte elevated gene-1 positively regulates the stability and function of forkhead box M1 during tumorigenesis.
Neoplasms
Metadherin: An emerging key regulator of the malignant progression of multiple cancers.
Neoplasms
Micheliolide ameliorates diabetic kidney disease by inhibiting Mtdh-mediated renal inflammation in type 2 diabetic db/db mice.
Neoplasms
MicroRNA-136 functions as a tumor suppressor in osteosarcoma via regulating metadherin.
Neoplasms
MicroRNA-154 inhibits the growth and metastasis of gastric cancer cells by directly targeting MTDH.
Neoplasms
MicroRNA-379 inhibits cell proliferation and invasion in glioma via targeting metadherin and regulating PTEN/AKT pathway.
Neoplasms
MicroRNA-559 plays an inhibitory role in the malignant progression of glioblastoma cells by directly targeting metadherin.
Neoplasms
microRNA-877 inhibits malignant progression of colorectal cancer by directly targeting MTDH and regulating the PTEN/Akt pathway.
Neoplasms
MicroRNA?216b inhibits cell proliferation and invasion in glioma by directly targeting metadherin.
Neoplasms
miR-145 inhibits tumor growth and metastasis by targeting metadherin in high-grade serous ovarian carcinoma.
Neoplasms
MiR-26a inhibits proliferation and migration of breast cancer through repression of MCL-1.
Neoplasms
MiR-302c inhibits tumor growth of hepatocellular carcinoma by suppressing the endothelial-mesenchymal transition of endothelial cells.
Neoplasms
MiR-302c-3p suppresses invasion and proliferation of glioma cells via down-regulating metadherin (MTDH) expression.
Neoplasms
MIR137/MIR2682 locus is associated with perineural invasiveness in head and neck cancer.
Neoplasms
MTDH and EphA7 are markers for metastasis and poor prognosis of gallbladder adenocarcinoma.
Neoplasms
MTDH and MAP3K1 are direct targets of apoptosis-regulating miRNAs in colorectal carcinoma.
Neoplasms
MTDH in macrophages promotes the vasculogenic mimicry via VEGFA-165/Flt-1 signaling pathway in head and neck squamous cell carcinoma.
Neoplasms
MTDH is an oncogene in multiple myeloma, which is suppressed by Bortezomib treatment.
Neoplasms
MTDH promotes metastasis of clear cell renal cell carcinoma by activating SND1-mediated ERK signaling and epithelial-mesenchymal transition.
Neoplasms
MTDH/AEG-1 downregulation using pristimerin-loaded nanoparticles inhibits Fanconi anemia proteins and increases sensitivity to platinum-based chemotherapy.
Neoplasms
Overcoming cisplatin resistance by targeting the MTDH-PTEN interaction in ovarian cancer with sera derived from rats exposed to Guizhi Fuling wan extract.
Neoplasms
Overexpression of microRNA-30a-5p inhibits liver cancer cell proliferation and induces apoptosis by targeting MTDH/PTEN/AKT pathway.
Neoplasms
Phenethyl Isothiocyanate Suppresses Stemness in the Chemo- and Radio-Resistant Triple-Negative Breast Cancer Cell Line MDA-MB-231/IR Via Downregulation of Metadherin.
Neoplasms
Post-trimodality expression levels of metadherin (MTDH) as a prognostic biomarker for esophageal adenocarcinoma patients.
Neoplasms
Prognostic significance of metadherin overexpression in hepatitis B virus-related hepatocellular carcinoma.
Neoplasms
Repression of metadherin inhibits biological behavior of prostate cancer cells and enhances their sensitivity to cisplatin.
Neoplasms
Silencing the expression of MTDH increases the radiation sensitivity of SKOV3 ovarian cancer cells and reduces their proliferation and metastasis.
Neoplasms
SU6668 modulates prostate cancer progression by downregulating MTDH/AKT signaling pathway.
Neoplasms
TAK1 Is a Novel Target in Hepatocellular Carcinoma and Contributes to Sorafenib Resistance.
Neoplasms
The essential role of MTDH in the progression of HCC: a study with immunohistochemistry, TCGA, meta-analysis and in vitro investigation.
Neoplasms
The FBXW7 tumor suppressor inhibits breast cancer proliferation and promotes apoptosis by targeting MTDH for degradation.
Neoplasms
The MTDH (-470G>A) polymorphism is associated with ovarian cancer susceptibility.
Neoplasms
The Oncogene Metadherin Modulates the Apoptotic Pathway Based on the Tumor Necrosis Factor Superfamily Member TRAIL (Tumor Necrosis Factor-related Apoptosis-inducing Ligand) in Breast Cancer.
Neoplasms
The targeting of MTDH by miR?145?5p or miR?145?3p is associated with prognosis and regulates the growth and metastasis of prostate cancer cells.
Neoplasms
Therapeutic Targeting of Metadherin Suppresses Colorectal and Lung Cancer Progression and Metastasis.
Neoplasms
TNFAIP2 expression induces epithelial-to-mesenchymal transition and confers platinum resistance in urothelial cancer cells.
Neoplasms
Transcriptional Repression of Raf Kinase Inhibitory Protein Gene by Metadherin during Cancer Progression.
Neoplasms
[Expression and clinical significance of MTDH and VEGF in triple-negative breast cancer].
Neoplasms
[Expression and clinical significance of MTDH, HIF-1? and TKTL1 in laryngeal carcinoma].
Neoplasms
[Expression of EphA7 and MTDH and clinicopathological significance in the squamous cell cancer of the tongue].
Neoplasms, Squamous Cell
[Expression of EphA7 and MTDH and clinicopathological significance in the squamous cell cancer of the tongue].
Neuroblastoma
Knockdown of MTDH sensitizes endometrial cancer cells to cell death induction by death receptor ligand TRAIL and HDAC inhibitor LBH589 co-treatment.
Neuroblastoma
Repression of metadherin inhibits biological behavior of prostate cancer cells and enhances their sensitivity to cisplatin.
Osteosarcoma
A polysaccharide from Trametes robiniophila Murrill induces apoptosis through intrinsic mitochondrial pathway in human osteosarcoma (U-2 OS) cells.
Osteosarcoma
Circular RNA Circ-03955 Promotes Epithelial-Mesenchymal Transition in Osteosarcoma by Regulating miR-3662/Metadherin Pathway.
Ovarian Neoplasms
Association of MTDH immunohistochemical expression with metastasis and prognosis in female reproduction malignancies: a systematic review and meta-analysis.
Ovarian Neoplasms
Mechanism of Low Expression of miR-30a-5p on Epithelial-Mesenchymal Transition and Metastasis in Ovarian Cancer.
Ovarian Neoplasms
Metadherin exon 11 skipping variant enhances metastatic spread of ovarian cancer.
Ovarian Neoplasms
miR-145 inhibits tumor growth and metastasis by targeting metadherin in high-grade serous ovarian carcinoma.
Ovarian Neoplasms
Overcoming cisplatin resistance by targeting the MTDH-PTEN interaction in ovarian cancer with sera derived from rats exposed to Guizhi Fuling wan extract.
Ovarian Neoplasms
Silencing the expression of MTDH increases the radiation sensitivity of SKOV3 ovarian cancer cells and reduces their proliferation and metastasis.
Ovarian Neoplasms
The MTDH (-470G>A) polymorphism is associated with ovarian cancer susceptibility.
Pancreatic Neoplasms
MiR-1297 suppresses pancreatic cancer cell proliferation and metastasis by targeting MTDH.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
mPGES-1/PGE2 promotes the growth of T-ALL cells in vitro and in vivo by regulating the expression of MTDH via the EP3/cAMP/PKA/CREB pathway.
Prostatic Hyperplasia
Repression of metadherin inhibits biological behavior of prostate cancer cells and enhances their sensitivity to cisplatin.
Prostatic Neoplasms
Genetic ablation of metadherin inhibits autochthonous prostate cancer progression and metastasis.
Prostatic Neoplasms
Knockdown of MTDH sensitizes endometrial cancer cells to cell death induction by death receptor ligand TRAIL and HDAC inhibitor LBH589 co-treatment.
Prostatic Neoplasms
Metadherin is an apoptotic modulator in prostate cancer through miR-342-3p regulation.
Prostatic Neoplasms
Repression of metadherin inhibits biological behavior of prostate cancer cells and enhances their sensitivity to cisplatin.
Prostatic Neoplasms
SU6668 modulates prostate cancer progression by downregulating MTDH/AKT signaling pathway.
Prostatic Neoplasms
The targeting of MTDH by miR?145?5p or miR?145?3p is associated with prognosis and regulates the growth and metastasis of prostate cancer cells.
Sarcoma
CIC-DUX sarcomas demonstrate frequent MYC amplification and ETS-family transcription factor expression.
Squamous Cell Carcinoma of Head and Neck
Hypoxia promotes migration/invasion and glycolysis in head and neck squamous cell carcinoma via an HIF-1?-MTDH loop.
Squamous Cell Carcinoma of Head and Neck
Increased expression of metadherin protein predicts worse disease-free and overall survival in laryngeal squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
MTDH in macrophages promotes the vasculogenic mimicry via VEGFA-165/Flt-1 signaling pathway in head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
[Expression and significance of MTDH and MMP-9 in laryngeal squamous cell carcinoma].
Stomach Neoplasms
circALPL Sponges miR-127 to Promote Gastric Cancer Progression by Enhancing MTDH Expression.
Stomach Neoplasms
Metadherin Promotes Malignant Phenotypes And Induces Beta-Catenin Nuclear Translocation And Epithelial-Mesenchymal Transition In Gastric Cancer.
Stomach Neoplasms
Metadherin regulates actin cytoskeletal remodeling and enhances human gastric cancer metastasis via epithelial-mesenchymal transition.
Stomach Neoplasms
MicroRNA-154 inhibits the growth and metastasis of gastric cancer cells by directly targeting MTDH.
Stomach Neoplasms
MicroRNA-197 inhibits gastric cancer progression by directly targeting metadherin.
Stomach Neoplasms
microRNA-22 acts as a metastasis suppressor by targeting metadherin in gastric cancer.
Stomach Neoplasms
miR?3664?5P suppresses the proliferation and metastasis of gastric cancer by attenuating the NF??B signaling pathway through targeting MTDH.
Thyroid Cancer, Papillary
Metadherin Expression is Associated with Extrathyroidal Extension in Papillary Thyroid Cancer Patients.
Tics
MTDH-SND1 interaction is crucial for expansion and activity of tumor-initiating cells in diverse oncogene- and carcinogen-induced mammary tumors.
Tongue Neoplasms
[Expression of EphA7 and MTDH and clinicopathological significance in the squamous cell cancer of the tongue].
Triple Negative Breast Neoplasms
A novel metadherin?7 splice variant enhances triple negative breast cancer aggressiveness by modulating mitochondrial function via NF?B-SIRT3 axis.
Triple Negative Breast Neoplasms
AMPK inhibits MTDH expression via GSK3? and SIRT1 activation: potential role in triple negative breast cancer cell proliferation.
Triple Negative Breast Neoplasms
SU6668 suppresses proliferation of triple negative breast cancer cells through down-regulating MTDH expression.
Triple Negative Breast Neoplasms
[Expression and clinical significance of MTDH and VEGF in triple-negative breast cancer].
Urinary Bladder Neoplasms
Long noncoding RNA OIP5-AS1 exhibits oncogenic activity in bladder cancer through miR-217 and MTDH.
Urinary Bladder Neoplasms
Metadherin is a novel prognostic marker for bladder cancer progression and overall patient survival.
Urologic Neoplasms
Metadherin in prostate, bladder, and kidney cancer: A systematic review.
Uterine Cervical Neoplasms
Association of MTDH immunohistochemical expression with metastasis and prognosis in female reproduction malignancies: a systematic review and meta-analysis.
Uterine Cervical Neoplasms
Metadherin confers chemoresistance of cervical cancer cells by inducing autophagy and activating ERK/NF-?B pathway.
Uterine Cervical Neoplasms
MicroRNA-433 inhibits cervical cancer progression by directly targeting metadherin to regulate the AKT and ?-catenin signalling pathways.
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