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(S)-3-quinuclidinol + NADP+ = 3-quinuclidinone + NADPH + H+
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3-quinuclidinone:NADP+ oxidoreductase ((S)-3-quinuclidinol-forming)
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3-quinuclidinone + NADPH + H+
(S)-3-quinuclidinol + NADP+
3-quinuclidinone + NADPH + H+
(S)-3-quinuclidinol + NADP+
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Substrates: stereospecific reduction of 3-quinuclidinone
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3-quinuclidinone + NADPH + H+
(S)-3-quinuclidinol + NADP+
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Substrates: stereospecific reduction of 3-quinuclidinone with over 99% enantiomeric excess, effects of concentration of 3-quinuclidinone hydrochloride, overview
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3-quinuclidinone + NADPH + H+
(S)-3-quinuclidinol + NADP+
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Substrates: stereospecific reduction of 3-quinuclidinone
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3-quinuclidinone + NADPH + H+
(S)-3-quinuclidinol + NADP+
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Substrates: stereospecific reduction of 3-quinuclidinone with over 99% enantiomeric excess, effects of concentration of 3-quinuclidinone hydrochloride, overview
?
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3-quinuclidinone + NADPH + H+
(S)-3-quinuclidinol + NADP+
3-quinuclidinone + NADPH + H+
(S)-3-quinuclidinol + NADP+
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Substrates: stereospecific reduction of 3-quinuclidinone
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3-quinuclidinone + NADPH + H+
(S)-3-quinuclidinol + NADP+
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Substrates: stereospecific reduction of 3-quinuclidinone
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additional information
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strain WY1406 utilizes most of the tested sugars, i.e. D-glucose, glycerol, maltose, sucrose, arabinose, sorbitol, except mannitol, for growth
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additional information
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strain WY1406 utilizes most of the tested sugars, i.e. D-glucose, glycerol, maltose, sucrose, arabinose, sorbitol, except mannitol, for growth
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Highest Expressing Human Cell Lines
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synthesis
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the enzyme can be used for synthesis of optically pure 3-quinuclidinol. Optically pure 3-quinuclidinol is an important intermediate for the synthesis of various anticholinergic drugs. (S)-3-Quinuclidinol is a very promising chiral building blocks for synthesis of serotonin receptor antagonist drugs and anticholinergic drugs
synthesis
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the enzyme can be used for synthesis of optically pure 3-quinuclidinol. Optically pure 3-quinuclidinol is an important intermediate for the synthesis of various anticholinergic drugs. (S)-3-Quinuclidinol is a very promising chiral building blocks for synthesis of serotonin receptor antagonist drugs and anticholinergic drugs
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Wang, Y.; Li, J.; Wu, Q.; Zhu, D.
Microbial stereospecific reduction of 3-quinuclidinone with newly isolated Nocardia sp. and Rhodococcus erythropolis
J. Mol. Catal. B
88
14-19
2013
Rhodococcus erythropolis, Rhodococcus erythropolis WY1406
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