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Requires K+ or NH4+ and Mn2+ or Co2+; also acts on (R)-malate.
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The enzyme appears in viruses and cellular organisms
beta,beta-dimethylmalate dehydrogenase, dehydrogenase, dimethylmalate, more
(R)-3,3-dimethylmalate + NAD+ = 3-methyl-2-oxobutanoate + CO2 + NADH
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