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Information on EC 1.1.1.44 - phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) and Organism(s) Oryza sativa and UniProt Accession Q9LI00

for references in articles please use BRENDA:EC1.1.1.44
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IUBMB Comments
The enzyme participates in the oxidative branch of the pentose phosphate pathway, whose main purpose is to produce NADPH and pentose for biosynthetic reactions. Highly specific for NADP+. cf. EC 1.1.1.343, phosphogluconate dehydrogenase (NAD+-dependent, decarboxylating).
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This record set is specific for:
Oryza sativa
UNIPROT: Q9LI00
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Word Map
The taxonomic range for the selected organisms is: Oryza sativa
The enzyme appears in selected viruses and cellular organisms
Synonyms
6pgd, 6-pgd, 6-p-gluconate dehydrogenase, os6pgdh1, 6-phospho-d-gluconate dehydrogenase, 6-phosphogluconate dehydrogenase (decarboxylating), llpdh, p6pgdh, tm0438, 6-phosphonogluconate dehydrogenase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
6-phosphonogluconate dehydrogenase
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6-phospho-D-gluconate dehydrogenase
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6-phosphogluconate dehydrogenase (decarboxylating)
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6-phosphogluconic carboxylase
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6-phosphogluconic dehydrogenase
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6PGDH
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GNTZII
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Os6PGDH2
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phosphogluconic acid dehydrogenase
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-
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
redox reaction
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oxidation
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reduction
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SYSTEMATIC NAME
IUBMB Comments
6-phospho-D-gluconate:NADP+ 2-oxidoreductase (decarboxylating)
The enzyme participates in the oxidative branch of the pentose phosphate pathway, whose main purpose is to produce NADPH and pentose for biosynthetic reactions. Highly specific for NADP+. cf. EC 1.1.1.343, phosphogluconate dehydrogenase (NAD+-dependent, decarboxylating).
CAS REGISTRY NUMBER
COMMENTARY hide
9073-95-4
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
6-phosphono-D-gluconate + NADP+
D-ribulose 5-phosphate + CO2 + NADPH
show the reaction diagram
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
6-phosphono-D-gluconate + NADP+
D-ribulose 5-phosphate + CO2 + NADPH
show the reaction diagram
one of the key enzymes in the pentose phosphate pathway, may be important for cell division and salt response
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COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
additional information
the enzyme is upregulated during salt stress
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pI VALUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
6.6
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calculated from sequence
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
cytosolic isozyme
SwissProt
Manually annotated by BRENDA team
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
low enzyme expression level
Manually annotated by BRENDA team
high enzyme expression level
Manually annotated by BRENDA team
very low enzyme expression level
Manually annotated by BRENDA team
low enzyme expression level
Manually annotated by BRENDA team
3-leaf stage
Manually annotated by BRENDA team
the enzyme is upregulated during salt stress
Manually annotated by BRENDA team
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transcript levels of both Os6PGDH1 and Os6PGDH2 are up-regulated in rice seedlings under drought, cold, high salinity and abscisic acid treatments
Manually annotated by BRENDA team
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
cytosolic isozyme
Manually annotated by BRENDA team
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
DNA and amino acid sequence determination and analysis
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Huang, J.; Zhang, H.; Wang, J.; Yang, J.
Molecular cloning and characterization of rice 6-phosphogluconate dehydrogenase gene that is up-regulated by salt stress
Mol. Biol. Rep.
30
223-227
2003
Oryza sativa (Q9LI00)
Manually annotated by BRENDA team
Hou, F.; Huang, J.; Yu, S.; Zhang, H.
The 6-phosphogluconate dehydrogenase genes are responsive to abiotic stresses in rice
J. Integr. Plant Biol.
49
655-663
2007
Oryza sativa
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Manually annotated by BRENDA team