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Information on EC 1.1.1.405 - ribitol-5-phosphate 2-dehydrogenase (NADP+)

for references in articles please use BRENDA:EC1.1.1.405
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IUBMB Comments
Requires Zn2+. The enzyme, characterized in bacteria, is specific for NADP. It is part of the synthesis pathway of CDP-ribitol. In Haemophilus influenzae it is part of a multifunctional enzyme also catalysing EC 2.7.7.40, D-ribitol-5-phosphate cytidylyltransferase. cf. EC 1.1.1.137, ribitol-5-phosphate 2-dehydrogenase.
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The enzyme appears in viruses and cellular organisms
Synonyms
ACS1, Bcs1, bifunctional ribulose 5-phosphate reductase/CDP-ribitol pyrophosphorylase, ribulose-5-P reductase, ribulose-5-phosphate reductase, TarIJ, TarJ, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
D-ribitol 5-phosphate + NADP+ = D-ribulose 5-phosphate + NADPH + H+
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