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Information on EC 1.1.1.387 - L-serine 3-dehydrogenase (NAD+)

for references in articles please use BRENDA:EC1.1.1.387

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IUBMB Comments

The enzyme, purified from the bacterium Pseudomonas aeruginosa, also shows activity with L-threonine (cf. EC 1.1.1.103, L-threonine 3-dehydrogenase). The enzyme has only very low activity with NADP+ [cf. EC 1.1.1.276, serine 3-dehydrogenase (NADP+)].

The expected taxonomic range for this enzyme is: Bacteria, Archaea

Synonyms
l-serdh, pa0743, l-serine 3-dehydrogenase, l-serine dehydrogenase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2-aminomalonate semialdehyde = 2-aminoacetaldehyde + CO2
show the reaction diagram
L-serine + NAD+ = 2-aminoacetaldehyde + CO2 + NADH + H+
show the reaction diagram
L-serine + NAD+ = 2-aminomalonate semialdehyde + NADH + H+
show the reaction diagram
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