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Information on EC - glucose/galactose 1-dehydrogenase

for references in articles please use BRENDA:EC1.1.1.360
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IUBMB Comments
A zinc protein. The enzyme from the archaeon Picrophilus torridus is involved in glucose and galactose catabolism via the nonphosphorylative variant of the Entner-Doudoroff pathway. It shows 20-fold higher activity with NADP+ compared to NAD+. The oxidation of D-glucose and D-galactose is catalysed at a comparable rate (cf. EC, glucose 1-dehydrogenase (NADP+) and EC, galactose 1-dehydrogenase (NADP+)).
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The expected taxonomic range for this enzyme is: Bacteria, Archaea, Eukaryota
dual-specific glucose/galactose dehydrogenase, GdhA, GlcDH, glucose (galactose) dehydrogenase, glucose/galactose dehydrogenase, TvGlcD, more
D-galactopyranose + NADP+ = D-galactono-1,5-lactone + NADPH + H+
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D-glucopyranose + NADP+ = D-glucono-1,5-lactone + NADPH + H+
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