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Information on EC 1.1.1.348 - (3R)-2'-hydroxyisoflavanone reductase

for references in articles please use BRENDA:EC1.1.1.348
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IUBMB Comments
This plant enzyme catalyses the penultimate step in the biosynthesis of the pterocarpin phytoalexins medicarpin and maackiain. This activity was previously classified as part of EC 1.1.1.246, pterocarpin synthase, which is now known to be catalysed by two enzymes, vestitone reductase and EC 4.2.1.139, medicarpin synthase.
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Word Map
The expected taxonomic range for this enzyme is: Medicago sativa
Synonyms
vestitone reductase, pterocarpan synthase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a (4R)-4,2'-dihydroxyisoflavan + NADP+ = a (3R)-2'-hydroxyisoflavanone + NADPH + H+
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