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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms dTDP-6-deoxy-L-lyxo-4-hexulose reductase, TAL, thymidine diphosphate-6-deoxy-L-lyxo-4-hexulose reductase, tll , more
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dTDP-6-deoxy-L-lyxo-4-hexulose reductase
thymidine diphosphate-6-deoxy-L-lyxo-4-hexulose reductase
dTDP-6-deoxy-L-lyxo-4-hexulose reductase
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dTDP-6-deoxy-L-lyxo-4-hexulose reductase
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dTDP-6-deoxy-L-lyxo-4-hexulose reductase
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TAL
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thymidine diphosphate-6-deoxy-L-lyxo-4-hexulose reductase
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thymidine diphosphate-6-deoxy-L-lyxo-4-hexulose reductase
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dTDP-6-deoxy-beta-L-talose + NAD(P)+ = dTDP-4-dehydro-beta-L-rhamnose + NAD(P)H + H+
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dTDP-6-deoxy-beta-L-talose:NAD(P)+ 4-oxidoreductase
The enzyme works equally well with NAD+ and NADP+.
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dTDP-6-deoxy-beta-L-lyxo-4-hexulose + NADH + H+
dTDP-6-deoxy-beta-L-talose + NAD+
dTDP-6-deoxy-L-glucose-lyxo-4-hexulose + NADH + H+
dTDP-6-deoxy-L-talose + NAD+
Substrates: - Products: -
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dTDP-6-deoxy-L-lyxo-4-hexulose + NADH + H+
dTDP-6-deoxy-beta-L-talose + NAD+
dTDP-6-deoxy-beta-L-lyxo-4-hexulose + NADH + H+
dTDP-6-deoxy-beta-L-talose + NAD+
Substrates: - Products: -
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dTDP-6-deoxy-beta-L-lyxo-4-hexulose + NADH + H+
dTDP-6-deoxy-beta-L-talose + NAD+
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Substrates: - Products: -
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dTDP-6-deoxy-L-lyxo-4-hexulose + NADH + H+
dTDP-6-deoxy-beta-L-talose + NAD+
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Substrates: - Products: -
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dTDP-6-deoxy-L-lyxo-4-hexulose + NADH + H+
dTDP-6-deoxy-beta-L-talose + NAD+
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Substrates: - Products: -
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NADH
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UniProt
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Highest Expressing Human Cell Lines
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Cell Line Links
Gene Links
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TAL_KITKI
318
0
33102
Swiss-Prot
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chitin bead chromatography and amylose column chromatography
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Ni-NTA agarose column chromatography
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expressed in Escherichia coli BL21 (DE3) cells
expressed in Escherichia coli BL21 cells
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expression in Escherichia coli
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Nakano, Y.; Suzuki, N.; Yoshida, Y.; Nezu, T.; Yamashita, Y.; Koga, T.
Thymidine diphosphate-6-deoxy-L-lyxo-4-hexulose reductase synthesizing dTDP-6-deoxy-L-talose from Actinobacillus actinomycetemcomitans
J. Biol. Chem.
275
6806-6812
2000
Aggregatibacter actinomycetemcomitans, Aggregatibacter actinomycetemcomitans NCTC 9710
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Karki, S.; Yoo, H.G.; Kwon, S.Y.; Suh, J.W.; Kwon, H.J.
Cloning and in vitro characterization of dTDP-6-deoxy-L-talose biosynthetic genes from Kitasatospora kifunensis featuring the dTDP-6-deoxy-L-lyxo-4-hexulose reductase that synthesizes dTDP-6-deoxy-L-talose
Carbohydr. Res.
345
1958-1962
2010
Kitasatospora kifunensis (E5F146), Kitasatospora kifunensis, Kitasatospora kifunensis MJM341
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