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Information on EC 1.1.1.336 - UDP-N-acetyl-D-mannosamine dehydrogenase and Organism(s) Yersinia pestis and UniProt Accession Q8ZAE4

for references in articles please use BRENDA:EC1.1.1.336
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IUBMB Comments
Part of the pathway for acetamido sugar biosynthesis in bacteria and archaea. The enzyme has no activity with NADP+.
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This record set is specific for:
Yersinia pestis
UNIPROT: Q8ZAE4
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The taxonomic range for the selected organisms is: Yersinia pestis
The expected taxonomic range for this enzyme is: Bacteria, Archaea
Synonyms
udp-n-acetyl-d-mannosamine dehydrogenase, mmp0706, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
UDP-ManNAc 6-dehydrogenase
-
-
-
-
wecC
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
UDP-N-acetyl-alpha-D-mannosamine:NAD+ 6-oxidoreductase
Part of the pathway for acetamido sugar biosynthesis in bacteria and archaea. The enzyme has no activity with NADP+.
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
UniProt
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
gene wecC is important for survival of Yersinia pestis in murine macrophages
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
WECC_YERPE
420
0
45639
Swiss-Prot
-
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Klein, K.A.; Fukuto, H.S.; Pelletier, M.; Romanov, G.; Grabenstein, J.P.; Palmer, L.E.; Ernst, R.; Bliska, J.B.
A transposon site hybridization screen identifies galU and wecBC as important for survival of Yersinia pestis in murine macrophages
J. Bacteriol.
194
653-662
2012
Yersinia pestis (Q8ZAE4), Yersinia pestis
Manually annotated by BRENDA team