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Information on EC 1.1.1.336 - UDP-N-acetyl-D-mannosamine dehydrogenase and Organism(s) Pseudomonas aeruginosa and UniProt Accession G3XD94

for references in articles please use BRENDA:EC1.1.1.336
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IUBMB Comments
Part of the pathway for acetamido sugar biosynthesis in bacteria and archaea. The enzyme has no activity with NADP+.
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This record set is specific for:
Pseudomonas aeruginosa
UNIPROT: G3XD94
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The taxonomic range for the selected organisms is: Pseudomonas aeruginosa
The expected taxonomic range for this enzyme is: Bacteria, Archaea
Synonyms
udp-n-acetyl-d-mannosamine dehydrogenase, mmp0706, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
UDP-ManNAc 6-dehydrogenase
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wecC
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SYSTEMATIC NAME
IUBMB Comments
UDP-N-acetyl-alpha-D-mannosamine:NAD+ 6-oxidoreductase
Part of the pathway for acetamido sugar biosynthesis in bacteria and archaea. The enzyme has no activity with NADP+.
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
specific knockout mutation in the UDP-D-Nacetylmannosamine dehydrogenase gene, wbpA, results in strains that no longer produce B-band lipopolysaccharide
PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
gene is not able to complement a defect in the Escherichia coli homologue wecC
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Burrows, L.L.; Pigeon, K.E.; Lam, J.S.
Pseudomonas aeruginosa B-band lipopolysaccharide genes wbpA and wbpI and their Escherichia coli homologues wecC and wecB are not functionally interchangeable
FEMS Microbiol. Lett.
189
135-141
2000
Pseudomonas aeruginosa (G3XD94)
Manually annotated by BRENDA team