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Information on EC 1.1.1.329 - 2-deoxy-scyllo-inosamine dehydrogenase

for references in articles please use BRENDA:EC1.1.1.329
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IUBMB Comments
Requires zinc. Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including kanamycin, neomycin and ribostamycin. cf. EC 1.1.99.38, 2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent).
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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
kanK, neoA, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2-deoxy-scyllo-inosamine + NAD(P)+ = 3-amino-2,3-dideoxy-scyllo-inosose + NAD(P)H + H+
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