Information on EC 1.1.1.287 - D-arabinitol dehydrogenase (NADP+)

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IUBMB Comments
The enzyme from the rust fungus Uromyces fabae can use D-arabinitol and D-mannitol as substrates in the forward direction and D-xylulose, D-ribulose and, to a lesser extent, D-fructose as substrates in the reverse direction. This enzyme carries out the reactions of both EC 1.1.1.11, D-arabinitol 4-dehydrogenase and EC 1.1.1.250, D-arabinitol 2-dehydrogenase, but unlike them, uses NADP+ rather than NAD+ as cofactor. D-Arabinitol is capable of quenching reactive oxygen species involved in defense reactions of the host plant.
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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
ARD1p, ArDH, D-arabitol dehydrogenase, D-arabitol dehydrogenase 1, More, NADP(+)-dependent D-arabitol dehydrogenase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
D-arabinitol + NADP+ = D-ribulose + NADPH + H+
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D-arabinitol + NADP+ = D-xylulose + NADPH + H+
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PATHWAY SOURCE
PATHWAYS
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