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Information on EC 1.1.1.28 - D-lactate dehydrogenase and Organism(s) Lactobacillus delbrueckii and UniProt Accession P26297

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Lactobacillus delbrueckii
UNIPROT: P26297 not found.
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Word Map
The taxonomic range for the selected organisms is: Lactobacillus delbrueckii
The expected taxonomic range for this enzyme is: Bacteria, Archaea, Eukaryota
Reaction Schemes
Synonyms
ldh, d-lactate dehydrogenase, d-ldh, paldh, fermentative lactate dehydrogenase, nad-dependent d-lactate dehydrogenase, d-nldh, ljd-ldh, d-(-)-lactate dehydrogenase, d-ldh82319, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
D-(-)-lactate dehydrogenase (NAD)
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D-lactate dehydrogenase
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D-lactic acid dehydrogenase
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D-lactic dehydrogenase
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D-LDH
D-specific lactic dehydrogenase
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dehydrogenase, D-lactate
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Fermentative lactate dehydrogenase
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lactic acid dehydrogenase
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LDH
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Respiratory D-lactate dehydrogenase
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
redox reaction
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oxidation
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reduction
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PATHWAY SOURCE
PATHWAYS
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-, -, -, -, -, -, -, -
SYSTEMATIC NAME
IUBMB Comments
(R)-lactate:NAD+ oxidoreductase
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CAS REGISTRY NUMBER
COMMENTARY hide
9028-36-8
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(R)-lactate + NAD+
pyruvate + NADH
show the reaction diagram
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-
?
pyruvate + NADH + H+
(R)-lactate + NAD+
show the reaction diagram
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
(R)-lactate + NAD+
pyruvate + NADH
show the reaction diagram
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?
pyruvate + NADH + H+
(R)-lactate + NAD+
show the reaction diagram
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r
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
iodoacetamide
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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
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activity of the recombinant enzyme in Corynebacerium glutamicum compared to the wild-type enzyme in Lactobacillus delbrueckii, overview
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
gene ldhA, expression in an enzyme-deficient ldhA-null Corynebacterium glutamicum strain resulting in increased production of D-lactate
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Garvie, E.I.
Bacterial lactate dehydrogenases
Microbiol. Rev.
44
106-139
1980
Klebsiella aerogenes, Leuconostoc mesenteroides, Eubacterium limosum, Escherichia coli, Lactobacillus acidophilus, Lactiplantibacillus plantarum, Levilactobacillus brevis, Lentilactobacillus buchneri, Lactobacillus delbrueckii subsp. bulgaricus, Lacticaseibacillus casei, Limosilactobacillus fermentum, Weissella confusa, Lactobacillus delbrueckii, Lactobacillus delbrueckii subsp. lactis, Lactobacillus jensenii, Lactobacillus jugurt-helveticus, Lactobacillus leichmannii, Lactobacillus vermiforme, Weissella viridescens, Lactococcus lactis, Leuconostoc mesenteroides subsp. cremoris, Leuconostoc mesenteroides subsp. dextranicum, Leuconostoc lactis, Oenococcus oeni, Weissella paramesenteroides, Mammalia, Staphylococcus aureus, Mycoplasma sp., Pediococcus acidilactici, Pediococcus damnosus, Pediococcus inopinatus, Pediococcus pentosaceus, Selenomonas ruminantium, Staphylococcus haemolyticus, Staphylococcus hominis, Staphylococcus sp., Staphylococcus warneri
Manually annotated by BRENDA team
Okino, S.; Suda, M.; Fujikura, K.; Inui, M.; Yukawa, H.
Production of D-lactic acid by Corynebacterium glutamicum under oxygen deprivation
Appl. Microbiol. Biotechnol.
78
449-454
2008
Escherichia coli, Lactobacillus delbrueckii
Manually annotated by BRENDA team