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IUBMB Comments Involved in the toluene-4-sulfonate degradation pathway in Comamonas testosteroni .
The enzyme appears in viruses and cellular organisms
Synonyms sulfobenzyl alcohol dehydrogenase, more
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sulfobenzyl alcohol dehydrogenase
sulfobenzyl alcohol dehydrogenase
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sulfobenzyl alcohol dehydrogenase
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4-(hydroxymethyl)benzenesulfonate + NAD+ = 4-formylbenzenesulfonate + NADH + H+
4-(hydroxymethyl)benzenesulfonate + NAD+ = 4-formylbenzenesulfonate + NADH + H+
involved in the toluene-4-sulfonate degradation pathway in Comamonas testeroni
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4-(hydroxymethyl)benzenesulfonate + NAD+ = 4-formylbenzenesulfonate + NADH + H+
Involved in the toluene-4-sulfonate degradation pathway
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MetaCyc
4-toluenesulfonate degradation I
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4-(hydroxymethyl)benzenesulfonate:NAD+ oxidoreductase
Involved in the toluene-4-sulfonate degradation pathway in Comamonas testosteroni.
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4-(hydroxymethyl)benzenesulfonate + NAD+
4-formylbenezenesulfonate + NADH
4-carboxybenzaldehyde + NADH
4-carboxybenzyl alcohol + NAD+
4-(hydroxymethyl)benzenesulfonate + NAD+
4-formylbenezenesulfonate + NADH
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Substrates: part of a specific transport system that mediates uptake of toluenesulfonat/toluenecarboxylate Products: -
r
4-(hydroxymethyl)benzenesulfonate + NAD+
4-formylbenezenesulfonate + NADH
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Substrates: part of a specific transport system that mediates uptake of toluenesulfonat/toluenecarboxylate Products: -
r
4-carboxybenzaldehyde + NADH
4-carboxybenzyl alcohol + NAD+
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Substrates: part of a specific transport system that mediates uptake of toluenesulfonat/toluenecarboxylate pathway of degradation Products: -
r
4-carboxybenzaldehyde + NADH
4-carboxybenzyl alcohol + NAD+
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Substrates: involved in the degradation of toluenesulfonate and toluenecarboxylate Products: -
r
4-carboxybenzaldehyde + NADH
4-carboxybenzyl alcohol + NAD+
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Substrates: involved in the degradation of toluenesulfonate and toluenecarboxylate Products: -
r
4-carboxybenzaldehyde + NADH
4-carboxybenzyl alcohol + NAD+
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Substrates: involved in the degradation of toluenesulfonate and toluenecarboxylate Products: -
r
4-carboxybenzaldehyde + NADH
4-carboxybenzyl alcohol + NAD+
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Substrates: part of a specific transport system that mediates uptake of toluenesulfonat/toluenecarboxylate pathway of degradation Products: -
r
4-carboxybenzaldehyde + NADH
4-carboxybenzyl alcohol + NAD+
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Substrates: involved in the degradation of toluenesulfonate and toluenecarboxylate Products: -
r
4-carboxybenzaldehyde + NADH
4-carboxybenzyl alcohol + NAD+
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Substrates: involved in the degradation of toluenesulfonate and toluenecarboxylate Products: -
r
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Fe2+
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2Fe-2S-Rieske center
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strain PSB-4: loss of reductase component to utilize p-toluenesulfonate to sulfobenzoate , strain TER-1: not able to utilize p-tolunenesulfonate and sulfobenzoate due to deletion of genetic material
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strain PSB-4: loss of reductase component to utilize p-toluenesulfonate to sulfobenzoate , strain TER-1: not able to utilize p-tolunenesulfonate and sulfobenzoate due to deletion of genetic material
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within a cluster of a four-gene operon, that defines a regulatory unit RI, that is involved in toluenesulfonate degradation
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within a cluster of a four-gene operon, that defines a regulatory unit RI, that is involved in toluenesulfonate degradation
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Highest Expressing Human Cell Lines
Filter by:
Cell Line Links
Gene Links
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TSAD1_COMTE
476
0
51011
Swiss-Prot
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TSAD2_COMTE
477
0
51082
Swiss-Prot
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A0A2N9B235_STRCX
465
0
48919
TrEMBL
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A0A514KKG2_9HYPH
248
0
26224
TrEMBL
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A0A6J4NNI3_9BURK
uncultured Ramlibacter sp
172
0
18240
TrEMBL
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A0A6J4KQA4_9HYPH
uncultured Microvirga sp
247
0
25806
TrEMBL
-
A0A1Y5TUL1_9RHOB
472
0
49893
TrEMBL
-
A0A3B0TIG9_9ZZZZ
248
0
26169
TrEMBL
other Location (Reliability: 5 )
A0A5C6BY78_9BACT
467
0
50380
TrEMBL
-
A0A5E6Z2H5_PSEFL
478
0
51120
TrEMBL
-
A0A1J5RPV9_9ZZZZ
485
0
50817
TrEMBL
other Location (Reliability: 3 )
A0A1D3K2H7_9PSED
478
0
51156
TrEMBL
-
A0A0D8FVS9_9ACTN
512
0
55626
TrEMBL
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A0A5E7ID47_PSEFL
478
0
51113
TrEMBL
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A0A090FMZ4_9HYPH
477
0
50729
TrEMBL
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A0A653S549_9HYPH
490
0
51057
TrEMBL
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A0A3B0RG40_9ZZZZ
130
0
13693
TrEMBL
Mitochondrion (Reliability: 3 )
A0A3B0T727_9ZZZZ
248
0
25807
TrEMBL
other Location (Reliability: 5 )
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51000
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2 * 51000, SDS-PAGE
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dimer
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2 * 51000, SDS-PAGE
dimer
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2 * 51000, SDS-PAGE
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additional information
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iron-sulfur flavoprotein
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to homogeneity, chromatography techniques
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Junker, F.; Saller, E.; Schläfli Oppenberg, H.R.; Kroneck, P.M.H.; Leisinger, T.; Cook, A.M.
Degradative pathways for p-toluenecarboxylate and p-toluenesulfonate and their multicomponent oxygenases in Comamonas testosteroni strains PSB-4 and T-2
Microbiology
142
2419-2427
1996
Comamonas testosteroni, Comamonas testosteroni T-2, Comamonas testosteroni TER-1:
brenda
Junker, F.; Kiewitz, R.; Cook, A.M.
Characterization of the p-toluenesulfonate operon tsaMBCD and tsaR in Comamonas testosteroni T-2
J. Bacteriol.
179
919-927
1997
Comamonas testosteroni, Comamonas testosteroni T-2
brenda
Schläfli Oppenberg, H.R.; Chen, G.; Leisinger, T.; Cook, A.M.
Regulation of the degradative pathways from 4-toluenesulphonate and 4-toluenecarboxylate to protocatechuate in Comamonas testosteroni T-2
Microbiology
141
1891-1899
1995
Comamonas testosteroni, Comamonas testosteroni T-2
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Locher, H.H.; Leisinger, T.; Cook, A.M.
4-Toluene sulfonate methyl-monooxygenase from Comamonas testosteroni T-2: Purification and asome properties of the oxygenase component
J. Bacteriol.
173
3741-3748
1991
Comamonas testosteroni
brenda
Locher, H.H.; Leisinger, T.; Cook, A.M.
Degradation of p-toluenesulphonic acid via sidechain oxidation, desulphonation and meta ring cleavage in Pseudomonas (Comamonas) testosteroni T-2
J. Gen. Microbiol.
135
1969-1978
1989
Comamonas testosteroni
brenda
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