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Information on EC 1.1.1.247 - codeinone reductase (NADPH)

for references in articles please use BRENDA:EC1.1.1.247

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IUBMB Comments

Catalyses the reversible reduction of codeinone to codeine, which is a direct precursor of morphine in the opium poppy plant, Papaver somniferum.

The enzyme appears in viruses and cellular organisms
Reaction Schemes

Synonyms
codeinone reductase, codeinone reductase (nadph), cor-b, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
codeine + NADP+ = codeinone + NADPH + H+
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
MetaCyc
morphine biosynthesis
Highest Expressing Human Cell Lines
Cell Line Links Gene Links