Information on EC 220.127.116.11 - 12beta-hydroxysteroid dehydrogenasefor references in articles please use BRENDA:EC18.104.22.168
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Acts on a number of bile acids, both in their free and conjugated forms.
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The expected taxonomic range for this enzyme is: Clostridium paraputrificum
12beta-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase, more
3alpha,7alpha,12beta-trihydroxy-5beta-cholan-24-oate + NADP+ = 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholan-24-oate + NADPH + H+
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