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L-histidinol + 2 NAD+ + H2O = L-histidine + 2 NADH + 2 H+
L-histidinol + 2 NAD+ + H2O = L-histidine + 2 NADH + 2 H+

bi uni uni bi ping pong mechanism, recombinant histidinol dehydrogenase
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L-histidinol + 2 NAD+ + H2O = L-histidine + 2 NADH + 2 H+
fast reversible oxidation of L-histidanol, followed by slow irreversible hydride transfer from the intermediate L-histidinal
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L-histidinol + 2 NAD+ + H2O = L-histidine + 2 NADH + 2 H+
also oxidizes L-histidinal
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L-histidinol + 2 NAD+ + H2O = L-histidine + 2 NADH + 2 H+
reaction mechanism, amino acid residues Glu326 and His327 are involved in catalysis
L-histidinol + 2 NAD+ + H2O = L-histidine + 2 NADH + 2 H+
bi uni uni bi ping-pong enzyme mechanism for MtHisD-catalyzed chemical reaction, involves abstraction of the hydroxyl group proton of L-histidinol by His336 and concomitant hydride transfer from the reactive carbon (carbon bound to the hydroxyl group that upon hydride transfer adopts the sp2 configuration) to NAD+, forming L-histidinaldehyde and transiently protonated His336
L-histidinol + 2 NAD+ + H2O = L-histidine + 2 NADH + 2 H+
enzyme HisD from Mycobacterium tuberculosis follows a bi uni uni bi ping-pong mechanism in which L-histidinol is the first substrate to bind and L-histidine the last product to dissociate, the amino acid side chains of His336 and Glu335 are likely involved in catalysis and/or substrate binding
L-histidinol + 2 NAD+ + H2O = L-histidine + 2 NADH + 2 H+
the enzyme catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine using a bi-uni-uni-bi ping pong kinetic mechanism
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L-histidinol + 2 NAD+ + H2O = L-histidine + 2 NADH + 2 H+
the enzyme catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine using a bi-uni-uni-bi ping pong kinetic mechanism
L-histidinol + 2 NAD+ + H2O = L-histidine + 2 NADH + 2 H+
the enzyme catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine using a bi-uni-uni-bi ping pong kinetic mechanism
L-histidinol + 2 NAD+ + H2O = L-histidine + 2 NADH + 2 H+
the enzyme catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine using a bi-uni-uni-bi ping pong kinetic mechanism
L-histidinol + 2 NAD+ + H2O = L-histidine + 2 NADH + 2 H+
the enzyme catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine using a bi-uni-uni-bi ping pong kinetic mechanism
L-histidinol + 2 NAD+ + H2O = L-histidine + 2 NADH + 2 H+
the enzyme catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine using a bi-uni-uni-bi ping pong kinetic mechanism
L-histidinol + 2 NAD+ + H2O = L-histidine + 2 NADH + 2 H+
the enzyme catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine using a bi-uni-uni-bi ping pong kinetic mechanism
L-histidinol + 2 NAD+ + H2O = L-histidine + 2 NADH + 2 H+
the enzyme catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine using a bi-uni-uni-bi ping pong kinetic mechanism
L-histidinol + 2 NAD+ + H2O = L-histidine + 2 NADH + 2 H+
the enzyme catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine using a bi-uni-uni-bi ping pong kinetic mechanism
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L-histidinol + 2 NAD+ + H2O = L-histidine + 2 NADH + 2 H+
enzyme HisD from Mycobacterium tuberculosis follows a bi uni uni bi ping-pong mechanism in which L-histidinol is the first substrate to bind and L-histidine the last product to dissociate, the amino acid side chains of His336 and Glu335 are likely involved in catalysis and/or substrate binding
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L-histidinol + 2 NAD+ + H2O = L-histidine + 2 NADH + 2 H+
the enzyme catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine using a bi-uni-uni-bi ping pong kinetic mechanism
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L-histidinol + 2 NAD+ + H2O = L-histidine + 2 NADH + 2 H+
bi uni uni bi ping-pong enzyme mechanism for MtHisD-catalyzed chemical reaction, involves abstraction of the hydroxyl group proton of L-histidinol by His336 and concomitant hydride transfer from the reactive carbon (carbon bound to the hydroxyl group that upon hydride transfer adopts the sp2 configuration) to NAD+, forming L-histidinaldehyde and transiently protonated His336
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-
L-histidinol + 2 NAD+ + H2O = L-histidine + 2 NADH + 2 H+
the enzyme catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine using a bi-uni-uni-bi ping pong kinetic mechanism
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L-histidinol + 2 NAD+ + H2O = L-histidine + 2 NADH + 2 H+
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L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 3 H+
L-histidinol + NAD+
L-histidinal + NADH + H+
additional information
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L-histidinal + NAD+ + H2O

L-histidine + NADH + H+
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L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
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reaction intermediate
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L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
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-
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L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
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reaction intermediate
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
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-
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
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reaction intermediate
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
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ir
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
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enzyme is responsible for catalysis of the terminal step in L-histidine biosynthesis, being performed in 2 sequential reactions via the intermediate L-histidinal
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ir
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
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L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
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-
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
-
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
-
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
-
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
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-
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
-
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
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-
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
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-
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
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-
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
-
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
-
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
-
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
-
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
-
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
-
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
-
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
-
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
-
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
-
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
-
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
-
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
-
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
-
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
-
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ir
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
ir
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
-
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
-
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
-
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
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?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
-
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
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?
L-histidinol + 2 NAD+ + H2O

L-histidine + 2 NADH + 2 H+
-
-
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?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
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?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
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?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
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?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
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?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
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?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
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?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
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?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
part of L-histidine biosynthesis
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-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
-
ir
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O

L-histidine + 2 NADH + 3 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 3 H+
-
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 3 H+
-
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 3 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 3 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 3 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 3 H+
two steps: NAD+-dependent oxidations of L-histidinol to L-histidinaldehyde and subsequently to L-histidine
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?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 3 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 3 H+
two steps: NAD+-dependent oxidations of L-histidinol to L-histidinaldehyde and subsequently to L-histidine
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-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 3 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 3 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 3 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 3 H+
the enzyme is highly specific for histidinol and NAD+
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?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 3 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 3 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 3 H+
via L-histidinaldehyde intermediate
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-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 3 H+
NAD+- and Zn+-dependent conversion of L-histidinol to L-histidine through an L-histidinaldehyde intermediate, leading to the concomitant reduction of 2 NAD+ molecules
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?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 3 H+
-
-
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?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 3 H+
NAD+- and Zn+-dependent conversion of L-histidinol to L-histidine through an L-histidinaldehyde intermediate, leading to the concomitant reduction of 2 NAD+ molecules
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?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 3 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 3 H+
via L-histidinaldehyde intermediate
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 3 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 3 H+
the enzyme is highly specific for histidinol and NAD+
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?
L-histidinol + NAD+

L-histidinal + NADH + H+
-
-
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ir
L-histidinol + NAD+
L-histidinal + NADH + H+
-
enzyme is responsible for catalysis of the terminal step in L-histidine biosynthesis, being performed in 2 sequential reactions via the intermediate L-histidinal
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ir
L-histidinol + NAD+
L-histidinal + NADH + H+
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ir
additional information

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active site binding structure for substrates L-histidinol, L-histamine, and L-histidine, NMR study
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additional information
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ligand-protein interactions in the active site of GcHDH, molecular docking, overview
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additional information
?
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ligand-protein interactions in the active site of GcHDH, molecular docking, overview
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additional information
?
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imidazole-containing substrate analogues are likely to bind to free enzyme
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?
additional information
?
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imidazole-containing substrate analogues are likely to bind to free enzyme
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?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 3 H+
L-histidinol + NAD+
L-histidinal + NADH + H+
-
enzyme is responsible for catalysis of the terminal step in L-histidine biosynthesis, being performed in 2 sequential reactions via the intermediate L-histidinal
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ir
L-histidinal + NAD+ + H2O

L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
enzyme is responsible for catalysis of the terminal step in L-histidine biosynthesis, being performed in 2 sequential reactions via the intermediate L-histidinal
-
-
ir
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
ir
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
-
reaction intermediate
-
?
L-histidinol + 2 NAD+ + H2O

L-histidine + 2 NADH + 2 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-
-
?
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
-
-