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BRENDA support

Information on EC 1.1.1.19 - glucuronate reductase

for references in articles please use BRENDA:EC1.1.1.19

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IUBMB Comments

Also reduces D-galacturonate. May be identical with EC 1.1.1.2 [alcohol dehydrogenase (NADP+)].

The enzyme appears in viruses and cellular organisms

Synonyms
akr1a1, aldehyde reductase ii, hexonate dehydrogenase, glucuronate reductase, d-glucuronate reductase, pcgor, galacturonate oxidoreductase, nadp-l-gulonate dehydrogenase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
L-gulonate + NADP+ = D-glucuronate + NADPH + H+
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
D-glucuronate degradation I, L-ascorbate biosynthesis IV (animals, D-glucuronate pathway), L-ascorbate biosynthesis VI (plants, myo-inositol pathway)