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Information on EC 1.1.1.168 - 2-dehydropantolactone reductase (Re-specific)

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IUBMB Comments
The yeast enzyme differs from that from Escherichia coli [EC 1.1.1.214 2-dehydropantolactone reductase (Si-specific)], which is specific for the Si-face of NADP+, and in receptor requirements from EC 1.1.99.26 3-hydroxycyclohexanone dehydrogenase.
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The enzyme appears in viruses and cellular organisms
Synonyms
(R)-pantoyl-lactone:NADP+ oxidoreductase (A-specific), 2-dehydropantoyl-lactone reductase, 2-dehydropantoyl-lactone reductase (A-specific), 2-ketopantoyl lactone reductase, ketopantoyl lactone reductase, reductase, 2-oxopantoyl lactone, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+
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PATHWAY SOURCE
PATHWAYS
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