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Information on EC 1.1.1.133 - dTDP-4-dehydrorhamnose reductase

for references in articles please use BRENDA:EC1.1.1.133

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IUBMB Comments

In the reverse direction, reduction on the 4-position of the hexose moiety takes place only while the substrate is bound to another enzyme that catalyses epimerization at C-3 and C-5; the complex has been referred to as dTDP-L-rhamnose synthase.

The enzyme appears in viruses and cellular organisms

Synonyms
4-ketoreductase, agl14, dtdp-4-dehydrorhamnose reductase, dtdp-6-deoxy-l-lyxo-4-hexulose reductase, dtdp-4-keto-l-rhamnose reductase, dtdp-4-keto-rhamnose reductase, thymidine diphosphate-4-dehydrorhamnose reductase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
dTDP-beta-L-rhamnose + NADP+ = dTDP-4-dehydro-beta-L-rhamnose + NADPH + H+
show the reaction diagram
Highest Expressing Human Cell Lines
Cell Line Links Gene Links