3.4.24.B3: matrix metalloproteinase-11

This is an abbreviated version!
For detailed information about matrix metalloproteinase-11, go to the full flat file.

Word Map on EC 3.4.24.B3

3.4.24.B3

metalloproteinases

metastasis

mmp-2

timps

gelatinase

microperoxidase-11

metamorphosis

tadpole

matrilysin

menstrual

medicine

stromelysin-2

microperoxidase

collagenase-3

pharmacology

diagnostics

Reaction

proteolytic degradation of proteins =

Synonyms

M10.007, matrix metalloproteinase 11, matrix metalloproteinase-11, matrix metalloproteinase-11/stromelysin-3, matrixin, matrixin 11, MMP stromelysin-3, MMP-11, MMP-11 proteinase, MMP11, More, MP-11, SL-3, ST-3, ST3, stromelysin 3, stromelysin-3

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.24 Metalloendopeptidases

3.4.24.B3 matrix metalloproteinase-11

Advanced search results

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
7	Activating Compound
6	AA Sequence
17	Application
1	CAS Registry Number
24	Cloned(Commentary)
2	Crystallization (Commentary)
1886	Disease/ Diagnostics
5	Expression
20	General Information
73	Inhibitors
53	Ki Value [mM]
12	KM Value [mM]
11	Localization
16	Metals/Ions
12	Molecular Weight [Da]
21	Natural Substrates/ Products (Substrates)
168	Organism
7	pH Optimum
9	Posttranslational Modification
21	Protein Variants
7	Purification (Commentary)
3	Reaction
14	Reaction Type
57	Reference
6	Renatured (Commentary)
91	Source Tissue
6	Specific Activity [micromol/min/mg]
86	Substrates and Products (Substrate)
12	Subunits
127	Synonyms
7	Temperature Optimum [°C]
16	Turnover Number [1/s]

Inhibitors

print visible entries

print all entries

Inhibitors on EC 3.4.24.B3 - matrix metalloproteinase-11

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide

Go to Inhibitor Search

1,10-phenanthroline

cephalosporin EK2900

EDTA

matrix metalloprotease inhibitor TIMP-2

2 entries

matrix metalloproteinase inhibitor AG3340

Homo sapiens

broad spectrum inhibitor

652423

matrix metalloproteinase inhibitor BB-94

Homo sapiens

651871

matrix metalloproteinase inhibitor TIMP-1

Mus musculus

complete inhibition, human

651843

matrix metalloproteinase inhibitor TIMP-2

Homo sapiens

651871

N-alpha-(2-[[(1-[[(4,6-dichloro-1H-indol-2-yl)carbonyl]amino]-2-phenylethyl)(hydroxy)phosphoryl]methyl]-5-phenylpentanoyl)-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-(2-[[(1-[[(6,8-dichloro-2-oxo-2H-chromen-3-yl)carbonyl]amino]-2-phenylethyl)(hydroxy)phosphoryl]methyl]-5-phenylpentanoyl)-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-(2-[[(1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl)(hydroxy)phosphoryl]methyl]-4-methylpentanoyl)-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-(2-[[(1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl)(hydroxy)phosphoryl]methyl]-4-naphthalen-2-ylbutanoyl)-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-(2-[[(1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl)(hydroxy)phosphoryl]methyl]-4-phenylbutanoyl)-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-(2-[[(1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl)(hydroxy)phosphoryl]methyl]-5-phenylpentanoyl)-D-tryptophanamide

Mus musculus

Q02853

1% residual activity at 0.002 mM

681751

N-alpha-(2-[[(1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl)(hydroxy)phosphoryl]methyl]-5-phenylpentanoyl)-L-tryptophanamide

Mus musculus

Q02853

RXP03

681751

N-alpha-(2-[[(1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl)(hydroxy)phosphoryl]methyl]-6-phenylhexanoyl)-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-(2-[[(1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl)(hydroxy)phosphoryl]methyl]tetradecanoyl)-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-(2-[[(1-[[(benzyloxy)carbonyl]amino]ethyl)(hydroxy)phosphoryl]methyl]-4-phenylbutanoyl)-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-(2-[[(1-[[(benzyloxy)carbonyl]amino]ethyl)(hydroxy)phosphoryl]methyl]-5-phenylpentanoyl)-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-(2-[[(1-[[3-(benzyloxy)propanoyl]amino]-2-phenylethyl)(hydroxy)phosphoryl]methyl]-5-phenylpentanoyl)-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-(2-[[(1-[[N-(3-chlorophenyl)-b-alanyl]amino]-2-phenylethyl)(hydroxy)phosphoryl]methyl]-5-phenylpentanoyl)-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-(2-[[(1-[[N-(5-chloro-2-hydroxyphenyl)-b-alanyl]amino]-2-phenylethyl)(hydroxy)phosphoryl]methyl]-5-phenylpentanoyl)-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-(3-[(1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl)(hydroxy)phosphoryl]-2-[[(4-methoxybenzyl)sulfanyl]methyl]propanoyl)-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-(3-[[(1S)-1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl](hydroxy)phosphoryl]-2-[(cyclohexylsulfanyl)methyl]propanoyl)-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-(3-[[(1S)-1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl](hydroxy)phosphoryl]-2-[(decylsulfanyl)methyl]propanoyl)-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-(3-[[(1S)-1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl](hydroxy)phosphoryl]-2-[(naphthalen-2-ylsulfanyl)methyl]propanoyl)-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-(3-[[(1S)-1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl](hydroxy)phosphoryl]-2-[[(2-ethoxy-2-oxoethyl)sulfanyl]methyl]propanoyl)-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-(3-[[(1S)-1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl](hydroxy)phosphoryl]-2-[[(2-methoxy-2-oxoethyl)sulfanyl]methyl]propanoyl)-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-(3-[[(1S)-1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl](hydroxy)phosphoryl]-2-[[(2-methylpropyl)sulfanyl]methyl]propanoyl)-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-(3-[[(1S)-1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl](hydroxy)phosphoryl]-2-[[(2-phenylethyl)sulfanyl]methyl]propanoyl)-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-(3-[[(1S)-1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl](hydroxy)phosphoryl]-2-[[(3-ethoxy-3-oxopropyl)sulfanyl]methyl]propanoyl)-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-(3-[[(1S)-1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl](hydroxy)phosphoryl]-2-[[(3-methoxy-3-oxopropyl)sulfanyl]methyl]propanoyl)-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-(3-[[(1S)-1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl](hydroxy)phosphoryl]-2-[[(3-methoxyphenyl)sulfanyl]methyl]propanoyl)-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-(3-[[(1S)-1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl](hydroxy)phosphoryl]-2-[[(3-methylbutyl)sulfanyl]methyl]propanoyl)-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-(3-[[(1S)-1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl](hydroxy)phosphoryl]-2-[[(4-chlorobenzyl)sulfanyl]methyl]propanoyl)-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-(3-[[(1S)-1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl](hydroxy)phosphoryl]-2-[[(4-methoxybenzyl)sulfanyl]methyl]propanoyl)-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-(3-[[(1S)-1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl](hydroxy)phosphoryl]-2-[[(furan-2-ylmethyl)sulfanyl]methyl]propanoyl)-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-[(2R)-3-[[(1S)-1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl](hydroxy)phosphoryl]-2-([[2-(1-methylethyl)phenyl]sulfanyl]methyl)propanoyl]-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-[(2R)-3-[[(1S)-1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl](hydroxy)phosphoryl]-2-([[2-(trifluoromethoxy)phenyl]sulfanyl]methyl)propanoyl]-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-[(2R)-3-[[(1S)-1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl](hydroxy)phosphoryl]-2-([[3-(trifluoromethoxy)biphenyl-4-yl]sulfanyl]methyl)propanoyl]-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-[(2R)-3-[[(1S)-1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl](hydroxy)phosphoryl]-2-([[4-bromo-2-(trifluoromethoxy)phenyl]sulfanyl]methyl)propanoyl]-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-[(2R)-3-[[(1S)-1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl](hydroxy)phosphoryl]-2-[(phenylsulfanyl)methyl]propanoyl]-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-[(2R)-3-[[(1S)-1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl](hydroxy)phosphoryl]-2-[[(2,4-di-tert-butylphenyl)sulfanyl]methyl]propanoyl]-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-[(2R)-3-[[(1S)-1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl](hydroxy)phosphoryl]-2-[[(2,5-dimethoxyphenyl)sulfanyl]methyl]propanoyl]-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-[(2R)-3-[[(1S)-1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl](hydroxy)phosphoryl]-2-[[(2-bromophenyl)sulfanyl]methyl]propanoyl]-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-[(2R)-3-[[(1S)-1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl](hydroxy)phosphoryl]-2-[[(2-ethylphenyl)sulfanyl]methyl]propanoyl]-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-[(2R)-3-[[(1S)-1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl](hydroxy)phosphoryl]-2-[[(2-methoxyphenyl)sulfanyl]methyl]propanoyl]-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-[2-([[1-(acetylamino)-2-phenylethyl](hydroxy)phosphoryl]methyl)-5-phenylpentanoyl]-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-[2-([[1-([N-[(benzyloxy)carbonyl]-D-alanyl]amino)-2-phenylethyl](hydroxy)phosphoryl]methyl)-5-phenylpentanoyl]-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-[2-([[1-([N-[(benzyloxy)carbonyl]-D-leucyl]amino)-2-phenylethyl](hydroxy)phosphoryl]methyl)-5-phenylpentanoyl]-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-[2-([[1-[[(benzyloxy)carbonyl]amino]-2-(3-bromophenyl)ethyl](hydroxy)phosphoryl]methyl)-5-phenylpentanoyl]-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-[2-benzyl-3-[(1-[[(benzyloxy)carbonyl]amino]ethyl)(hydroxy)phosphoryl]propanoyl]-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-[2-[(hydroxy[1-[(1H-indol-2-ylcarbonyl)amino]-2-phenylethyl]phosphoryl)methyl]-5-phenylpentanoyl]-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-[2-[(hydroxy[2-phenyl-1-[(N-phenyl-b-alanyl)amino]ethyl]phosphoryl)methyl]-5-phenylpentanoyl]-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-[2-[(hydroxy[2-phenyl-1-[(quinolin-2-ylcarbonyl)amino]ethyl]phosphoryl)methyl]-5-phenylpentanoyl]-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-[3-(benzyloxy)-2-[[(1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl)(hydroxy)phosphoryl]methyl]propanoyl]-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-[3-(benzyloxy)-2-[[(1-[[(benzyloxy)carbonyl]amino]ethyl)(hydroxy)phosphoryl]methyl]propanoyl]-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-[3-[(1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl)(hydroxy)phosphoryl]-2-(naphthalen-2-ylmethyl)propanoyl]-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-[3-[(1-[[(benzyloxy)carbonyl]amino]ethyl)(hydroxy)phosphoryl]-2-methylpropanoyl]-L-tryptophanamide

Mus musculus

Q02853

681751

N-alpha-[3-[(1-[[(benzyloxy)carbonyl]amino]ethyl)(hydroxy)phosphoryl]-2-[(benzylsulfanyl)methyl]propanoyl]-L-tryptophanamide

Mus musculus

Q02853

681751

N2-(2-[[(1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl)(hydroxy)phosphoryl]methyl]-5-phenylpentanoyl)-3-[(3,5-dinitrophenyl)amino]-L-alaninamide

Mus musculus

Q02853

681751

N2-(2-[[(1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl)(hydroxy)phosphoryl]methyl]-5-phenylpentanoyl)-L-alaninamide

Mus musculus

Q02853

20% residual activity at 0.002 mM

681751

phenylmethylsulfonyl fluoride

Mus musculus

slight inhibition

651843

phosphinic inhibitor

2 entries

TIMP-1

Canis lupus familiaris

D6R1X0

tissue inhibitor of metalloproteinases

733960

additional information

2 entries