3.4.24.59: mitochondrial intermediate peptidase
This is an abbreviated version!
For detailed information about mitochondrial intermediate peptidase, go to the full flat file.
Word Map on EC 3.4.24.59
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3.4.24.59
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mpp
-
presequence
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oct1
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mating-type
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tetrapolarity
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schizophyllum
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homobasidiomycetes
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heterothallic
- 3.4.24.59
- mpp
- presequence
- oct1
-
mating-type
-
tetrapolarity
-
schizophyllum
- homobasidiomycetes
-
heterothallic
Reaction
release of an N-terminal octapeptide as second stage of processing of some proteins imported into the mitochondrion =
Synonyms
At1g09300, hMIP, Icp55, MIP, MIP1, MIPEP, mitochondrial intermediate peptidase, OCT1, octapeptidyl aminopeptidase 1, Proteinase, mitochondrial intermediate precursor-processing
ECTree
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Reference
Reference on EC 3.4.24.59 - mitochondrial intermediate peptidase
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Isaya, G.; Kalousek, F.; Rosenberg, L.E.
Amino-terminal octapeptides function as recognition signals for the mitochondrial intermediate peptidase
J. Biol. Chem.
267
7904-7910
1992
Rattus norvegicus
Isaya, G.; Kalousek, F.; Rosenberg, L.E.
Sequence analysis of rat mitochondrial intermediate peptidase: similarity to zinc metallopeptidases and to a putative yeast homologue
Proc. Natl. Acad. Sci. USA
89
8317-8321
1992
Rattus norvegicus
Isaya, G.; Miklos, D.; Rollins, R.A.
MIP1, a new yeast gene homologous to the rat mitochondrial intermediate peptidase gene, is required for oxidative metabolism in Saccharomyces cerevisiae
Mol. Cell. Biol.
14
5603-5616
1994
Saccharomyces cerevisiae
Isaya, G.; Kalousek, F.
Mitochondrial intermediate peptidase
Methods Enzymol.
248
556-567
1995
Rattus norvegicus
Kalousek, F.; Isaya, G.; Rosenberg, L.E.
Rat liver mitochondrial intermediate peptidase (MIP): purification and initial characterization
EMBO J.
11
2803-2809
1992
Rattus norvegicus
Branda, S.S.; Isaya, G.
Prediction and identification of new natural substrates of the yeast mitochondrial intermediate peptidase
J. Biol. Chem.
270
27366-27373
1995
Saccharomyces cerevisiae
Isaya, G.
Mitochondrial intermediate peptidase
Handbook Of Proteolytic Enzymes(Barrett,A. J. ,Rawlings,N. D. ,Woessner,J. F. ,Eds. )Academic Press
1
366-369
2004
Saccharomyces cerevisiae, Homo sapiens, Mus musculus, Rattus norvegicus, Schizophyllum commune
-
Hervouet, E.; Pecina, P.; Demont, J.; Vojtiskova, A.; Simonnet, H.; Houstek, J.; Godinot, C.
Inhibition of cytochrome c oxidase subunit 4 precursor processing by the hypoxia mimic cobalt chloride
Biochem. Biophys. Res. Commun.
344
1086-1093
2006
Homo sapiens
van der Nest, M.A.; Slippers, B.; Stenlid, J.; Wilken, P.M.; Vasaitis, R.; Wingfield, M.J.; Wingfield, B.D.
Characterization of the systems governing sexual and self-recognition in the white rot homobasidiomycete Amylostereum areolatum
Curr. Genet.
53
323-336
2008
Amylostereum areolatum
Marcondes, M.; Torquato, R.; Assis, D.; Juliano, M.; Hayashi, M.; Oliveira, V.
Mitochondrial intermediate peptidase: Expression in Escherichia coli and improvement of its enzymatic activity detection with FRET substrates
Biochem. Biophys. Res. Commun.
391
123-128
2010
Homo sapiens
Lee, S.F.; Srinivasan, B.; Sephton, C.F.; Dries, D.R.; Wang, B.; Yu, C.; Wang, Y.; Dewey, C.M.; Shah, S.; Jiang, J.; Yu, G.
Gamma-secretase-regulated proteolysis of the Notch receptor by mitochondrial intermediate peptidase
J. Biol. Chem.
286
27447-27453
2011
Homo sapiens
Voegtle, F.N.; Prinz, C.; Kellermann, J.; Lottspeich, F.; Pfanner, N.; Meisinger, C.
Mitochondrial protein turnover: role of the precursor intermediate peptidase Oct1 in protein stabilization
Mol. Biol. Cell
22
2135-2143
2011
Saccharomyces cerevisiae
Teixeira, P.; Glaser, E.
Processing peptidases in mitochondria and chloroplasts
Biochim. Biophys. Acta
1833
360-370
2013
Rattus norvegicus
Carrie, C.; Venne, A.; Zahedi, R.; Soll, J.
Identification of cleavage sites and substrate proteins for two mitochondrial intermediate peptidases in Arabidopsis thaliana
J. Exp. Bot.
66
2691-2708
2015
Arabidopsis thaliana (W6HYK5), Arabidopsis thaliana
Marcondes, M.F.; Alves, F.M.; Assis, D.M.; Hirata, I.Y.; Juliano, L.; Oliveira, V.; Juliano, M.A.
Substrate specificity of mitochondrial intermediate peptidase analysed by a support-bound peptide library
FEBS open bio
5
429-436
2015
Homo sapiens
Huang, S.; Nelson, C.J.; Li, L.; Taylor, N.L.; Stroeher, E.; Peteriet, J.; Millar, A.H.
Intermediate claevage peptidase55 modifies enzyme amino termini and alters protein stability in Arabidopsis mitochondria
Plant Physiol.
168
415-427
2015
Arabidopsis thaliana (F4HZG9)
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