3.4.24.38: gametolysin
This is an abbreviated version!
For detailed information about gametolysin, go to the full flat file.
Word Map on EC 3.4.24.38
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3.4.24.38
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autolysins
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pneumococcal
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mating-type
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n-acetylmuramidase
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degradation
- 3.4.24.38
- autolysins
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pneumococcal
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mating-type
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n-acetylmuramidase
- degradation
Reaction
Cleavage of the proline- and hydroxyproline-rich proteins of the Chlamydomonas cell wall; also cleaves azocasein, gelatin and Leu-Trp-Met-/-Arg-Phe-Ala =
Synonyms
cell wall lytic enzyme, Chlamydomonas cell wall degrading protease, Chlamydomonas reinhardtii metalloproteinase, g-lysin, Gamete autolysin, Gamete lytic enzyme, Gametolysin, GLE, mmp1
ECTree
3.4.24.38 gametolysinAdvanced search results
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results (Inhibitors
Inhibitors on EC 3.4.24.38 - gametolysin
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INHIBITOR 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
tosyl-Lys chloromethyl ketone
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2 mM, less efficient than tosyl-Phe-chloromethyl ketone
EDTA
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inactivation by dialysis, 1-2 mM Zn2+, Mn2+ or Co2+ restores activity of metall-free apoenzyme to 0.5%, 10% and 50% of native enzyme, respectively, no restoring by Mg2+, Ca2+, Cu2+ or Fe3+; most effectively reversed by Co2+
additional information
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no inhibition by trypsin inhibitor, 6-aminohexanoic acid; pepstatin A
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additional information
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chymostatin, antipain, leupeptin; pepstatin A; various amino acids, protease inhibitor E-64
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additional information
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chymostatin, antipain, leupeptin; pepstatin A
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