3.4.22.B60: cathepsin L2

This is an abbreviated version!
For detailed information about cathepsin L2, go to the full flat file.

Reaction

preference for Arg in the P1 position, Pro is accepted in the P2 position =

Synonyms

cathepsin L2, cathepsin L2 protease, CatL2, CL2, FhCatL2, FhCL2, FhpCL2

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.22 Cysteine endopeptidases

                3.4.22.B60 cathepsin L2

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Results	in table
1	Activating Compound
4	AA Sequence
2	Application
5	Cloned(Commentary)
40	Disease/ Diagnostics
2	Expression
6	General Information
8	Inhibitors
8	kcat/KM [mM/s]
4	Ki Value [mM]
33	KM Value [mM]
4	Localization
4	Molecular Weight [Da]
14	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
155	Organism
1	pH Optimum
3	Posttranslational Modification
1	Protein Variants
6	Purification (Commentary)
1	Reaction
16	Reference
1	Renatured (Commentary)
10	Source Tissue
2	Specific Activity [micromol/min/mg]
48	Substrates and Products (Substrate)
4	Subunits
17	Synonyms
1	Temperature Optimum [°C]
33	Turnover Number [1/s]

Cloned

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Cloned on EC 3.4.22.B60 - cathepsin L2

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CLONED (Commentary)

ORGANISM

UNIPROT

LITERATURE

expressed in Pichia angusta

Fasciola hepatica

-

718252

expression in Saccharomyces cerevisiae

Fasciola hepatica

-

695026

gene FhpCL2, DNA and amino acid sequence determination and analysis, sequence comparisons of rFhpCLs, recombinant expression of His-tagged enzyme in Escherichia coli

Fasciola hepatica

A0A220T1Z2

754983

real-time PCR enzyme expression analysis

Mus musculus

-

753117

recombinantly expressed in Pichia pastoris

Fasciola hepatica

Q24940

680930