3.4.22.6: chymopapain
This is an abbreviated version!
For detailed information about chymopapain, go to the full flat file.
Word Map on EC 3.4.22.6
-
3.4.22.6
-
chemonucleolysis
-
disc
-
lumbar
-
herniated
-
intervertebral
-
intradiscal
-
pulposus
-
sciatica
-
proteinases
-
anaphylaxis
-
percutaneous
-
proteoglycans
-
latex
-
anaphylactic
-
spine
-
nucleolysis
-
radicular
-
microdiscectomy
-
immunomagnetic
-
decompress
-
myelography
-
hernia
-
prick
-
keratan
-
bromelain
-
chondroitinase
-
caricain
-
diskectomy
-
fibrosus
-
ficin
-
dura
-
prolapsed
-
discogenic
-
anulus
-
low-back
-
actinidin
-
myelogram
-
nutrition
-
medicine
-
3.4.22.2
- 3.4.22.6
-
chemonucleolysis
- disc
-
lumbar
-
herniated
-
intervertebral
-
intradiscal
- pulposus
- sciatica
- proteinases
- anaphylaxis
-
percutaneous
- proteoglycans
- latex
-
anaphylactic
- spine
-
nucleolysis
-
radicular
-
microdiscectomy
-
immunomagnetic
-
decompress
-
myelography
-
hernia
-
prick
- keratan
- bromelain
- chondroitinase
- caricain
-
diskectomy
- fibrosus
- ficin
-
dura
-
prolapsed
-
discogenic
-
anulus
-
low-back
- actinidin
-
myelogram
- nutrition
- medicine
-
3.4.22.2
Reaction
Similar to that of papain =
Synonyms
Chymopapain, chymopapain A, chymopapain B, chymopapain isoform II, chymopapain isoform III, chymopapain isoform IV, Chymopapain S, CpXCP8, EC 3.4.4.11, More, papaya proteinase II, PPII
ECTree
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pH Optimum
pH Optimum on EC 3.4.22.6 - chymopapain
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4.91
assay at. Chymopapain shows the best activity and enantioselectivity in the presence of phosphate buffer (pH 4.91, buffer/MeCN:0.12, v/v), which give the product in yield of 45% with 72:28 (anti/syn ratio) and 78% ee (for anti isomer)
6.2
7.2
additional information
pH value of the reaction medium plays a significant role in maintaining the stability and catalytic activity of the enzyme
7.2
enzyme is dissolved in phosphate buffer and used with a suspension of lysosomes in 0.154 mol/l sodium chloride