3.4.19.12: ubiquitinyl hydrolase 1

This is an abbreviated version!
For detailed information about ubiquitinyl hydrolase 1, go to the full flat file.

Word Map on EC 3.4.19.12

3.4.19.12

nerve

proteasome

neurodegenerative

fiber

innervation

deubiquitinase

polyglutamine

ataxia

parkinsonism

spinocerebellar

ubiquitin-proteasome

polyubiquitinated

glial

sars-cov-2

coronavirus

covid-19

calcitonin

neurofilament

fibrillary

neuropeptide

neuron-specific

traumatic

gene-related

cyld

parkin

polyq

synaptophysin

ubiquitin-like

polyproteins

usp7

ubiquitin-dependent

alpha-synuclein

deubiquitylating

npy

myenteric

3clpro

monoubiquitination

nedd8

cd45ro

isg15

intraepidermal

k48-linked

spermatogonial

mono-ubiquitinated

ubiquitin-binding

3c-like

mers-cov

medicine

isopeptide

degradation

synthesis

diagnostics

anti-sars-cov-2

molecular biology

analysis

concussion

pharmacology

drug development

Reaction

Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal) =

Synonyms

A20, AD-019, AMSH, associated molecule with the SH3-domain of STAM, AT-3, ataxin-3, BAP1, BPLF1, BRCA1-associated protein-1, C-terminal hydrolases UCHL3, C-terminal ubiquitin hydrolase, Cezanne, CGI-70, CYLD, de-ubiquitinating enzyme, deubiquinating isopeptidase T, deubiquitinating enzyme, Doa4, Doa4 ubiquitin hydrolase, Doa4p ubiquitin isopeptidase, DUB, dUCH, EC 3.1.2.15, esterase, ubiquitin thiol-, hydrolase, ubiquitin carboxyl-terminal, hydrolase, ubiquitin carboxyl-terminal (Aplysia californica gene Ap-uch), Iso-T, isopeptidase, isopeptidase T, More, Neuron cytoplasmic protein 9.5, neuronal-specific protein gene product 9.5, OsUCH1, OsUCH2, OsUCH3, OsUCH4, OsUCH5, OTU-1, OTUB1, OTUB2, Otubain-1, Otubain-2, ovarian tumour 1, PA-700 associated isopeptidase, papain-like protease, PGP 9.5, PGP 9.5/UCHL1, PGP9.5, PGP9.5.1, PLP2, PLpro, Ub isopeptidase, ubiquitin C terminal hydrolase 1, ubiquitin C-terminal hydrolase, ubiquitin C-terminal hydrolase (Aplysia californica gene Ap-uch), ubiquitin C-terminal hydrolase 1, ubiquitin C-terminal hydrolase 37, ubiquitin C-terminal hydrolase 8, ubiquitin C-terminal hydrolase isoform L3, ubiquitin C-terminal hydrolase L-1, ubiquitin C-terminal hydrolase L1, ubiquitin C-terminal hydrolase L3, Ubiquitin C-terminal hydrolase UCH37, ubiquitin C-terminal hydrolase-1, ubiquitin C-terminal hydrolase-L1, ubiquitin C-terminal hydrolase-L3, ubiquitin C-terminal hydrolase-L5, ubiquitin C-terminal hydrorase-L1, ubiquitin carboxy terminal hydrolase-L1, ubiquitin carboxy terminal hydrolase-L3, ubiquitin carboxy-terminal hydrolase, ubiquitin carboxy-terminal hydrolase 1, ubiquitin carboxy-terminal hydrolase L1, ubiquitin carboxy-terminal hydrolase-L1, ubiquitin carboxy-terminal hydrolase-L3, ubiquitin carboxyhydrolase L3, ubiquitin carboxyl terminal esterase L1, ubiquitin carboxyl terminal hydrolase 1, ubiquitin carboxyl terminal hydrolase L1, ubiquitin carboxyl terminal hydrolase-L1, ubiquitin carboxyl-terminal hydrolase, ubiquitin carboxyl-terminal hydrolase 1, ubiquitin carboxyl-terminal hydrolase 44, ubiquitin carboxyl-terminal hydrolase isozyme L1, ubiquitin carboxyl-terminal hydrolase L-1, ubiquitin carboxyl-terminal hydrolase L1, ubiquitin carboxyl-terminal hydrolase l3, ubiquitin carboxyl-terminal hydrolase L5, ubiquitin carboxyl-terminal hydrolase-L1, ubiquitin carboxyl-terminal hydrolase-L5, ubiquitin carboxyterminal hydrolase L1, ubiquitin carboxyterminal hydrolase L3, ubiquitin carboxyterminal hydrolase-L1, ubiquitin hydrolase, ubiquitin hydrolase Uch-L1, ubiquitin hydrolase UCH-L3, ubiquitin isopeptidase, Ubiquitin thiolesterase, Ubiquitin thiolesterase L1, Ubiquitin thiolesterase L3, Ubiquitin thiolesterase L4, Ubiquitin thiolesterase L5, ubiquitin-C-terminal hydrolase L1, ubiquitin-carboxyl-terminal hydrolase PGP-9.5, ubiquitin-specific protease 44, UBPY, UCH, UCH L-1, UCH L1, UCH-1, UCH-8, UCH-L1, UCH-L2, UCH-L3, UCH-L4, UCH-L5, UCH37, UCH54, UCHL-1, UCHL-3, UCHL1, UCHL1/PGP 9.5, UCHL2, Uchl3, UCHL5, UCHL5N240, USP19, USP22, USP44, yeast ubiquitin hydrolase, YUH, YUH1

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.19 Omega peptidases

3.4.19.12 ubiquitinyl hydrolase 1

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Results	in table
34	Activating Compound
102795	AA Sequence
56	Application
2	CAS Registry Number
64	Cloned(Commentary)
8	Crystallization (Commentary)
8472	Disease/ Diagnostics
18	Expression
94	General Information
2	General Stability
54	IC50 Value
161	Inhibitors
8	kcat/KM [mM/s]
31	Ki Value [mM]
63	KM Value [mM]
74	Localization
15	Metals/Ions
33	Molecular Weight [Da]
85	Natural Substrates/ Products (Substrates)
386	Organism
4	Oxidation Stability
825	PDB ID
29	pH Optimum
3	pH Range
3	pI Value
5	Posttranslational Modification
151	Protein Variants
41	Purification (Commentary)
3	Reaction
1	Reaction Type
218	Reference
1	Renatured (Commentary)
454	Source Tissue
18	Specific Activity [micromol/min/mg]
3	Storage Stability
284	Substrates and Products (Substrate)
32	Subunits
468	Synonyms
21	Temperature Optimum [°C]
1	Temperature Range [°C]
4	Temperature Stability [°C]
49	Turnover Number [1/s]

Synonyms

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Synonyms on EC 3.4.19.12 - ubiquitinyl hydrolase 1

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A20