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3.1.22.1: deoxyribonuclease II

This is an abbreviated version!
For detailed information about deoxyribonuclease II, go to the full flat file.

Word Map on EC 3.1.22.1

Reaction

endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotide end-products =

Synonyms

acid deoxyribonuclease, acid DNase, crn-7, deoxyribonuclease II, deoxyribonuclease IIalpha, deoxyribonuclease IIbeta, deoxyribonucleate 3'-nucleotidohydrolase, DNase 2, DNase 2a, DNase II, DNase II homolog, DNase II-1, DNase II-7, DNase IIalpha, DNase IIb, DNase IIbeta, EC 3.1.4.6, L-DNase II, LEI, LEI-derived DNase II, LEI/L-DNase II, leukocyte elastase inhibitor-derived DNase II, leukocyte elastase inhibitor/LEI-derived DNase II, lysosomal DNase II, Nuc-1, NUC-1 apoptotic nuclease, pancreatic DNase II, plancitoxin 1, R31240_2, Sjda, TsDNase II-1, TsDNase II-7

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.22 Endodeoxyribonucleases producing 3'-phosphomonoesters
                3.1.22.1 deoxyribonuclease II

pH Range

pH Range on EC 3.1.22.1 - deoxyribonuclease II

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pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
3.5 - 6.5
-
-
4 - 7.5
-
pH 4.0: about 30% of maximal activity, pH 7.5: about 45% of maximal activity
4.7
-
hydrolyzes DNA under acidic conditions
5 - 6.8
-
pH 5.0: about 40% of maximal activity, pH 6.8: about 15% of maximal activity
7 - 8
pH 7.0: about 65% of maximal activity, pH 8.0: about 40% of maximnal activity
7.2
-
no activity above