Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.1.1.6: catechol O-methyltransferase

This is an abbreviated version!
For detailed information about catechol O-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.6

Reaction

S-adenosyl-L-methionine
+
a catechol
=
S-adenosyl-L-homocysteine
 +
a guaiacol

Synonyms

catechol methyltransferase, catechol-O-methyl transferase, catechol-O-methyl transferase, membrane bound, catechol-O-methyl transferase, soluble, catechol-O-methyltransferase, catechol-O-transferase, catecholamine O-methyltransferase, COMT, COMT I, COMT II, COMT-mb, COMT-s, COMT1, COMT2, CTOMT1, L-COMT, MB-COMT, methyltransferase, catechol, S-COMT, SCOMT

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.6 catechol O-methyltransferase

Turnover Number

Turnover Number on EC 2.1.1.6 - catechol O-methyltransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.085 - 0.99
2-hydroxyestradiol
0.1
4-hydroxyequilenin
-
pH 7.8
0.035 - 0.077
4-hydroxyestradiol
0.18 - 0.26
catechin
9.67
catechol
-
pH 7.5, 25°C
0.088 - 0.19
dopamine
0.17 - 0.315
epicatechin
0.085 - 0.25
epinephrine
0.0289
esculetin
pH 7.5, temperature not specified in the publication
0.04 - 0.18
norepinephrine