2.1.1.104: caffeoyl-CoA O-methyltransferase

This is an abbreviated version!
For detailed information about caffeoyl-CoA O-methyltransferase, go to the full flat file.

Reaction

Synonyms

ASCCoAOMT, At4g26220, caffeic acid 3-O-methyltransferase, caffeoyl CoA 3-O-methyltransferase, caffeoyl CoA methyltransferase, caffeoyl CoA methyltransferase 7, caffeoyl CoA O-methyltransferase, caffeoyl CoA-O-methyltransferase, caffeoyl coenzyme A 3-O-methyltransferase, caffeoyl coenzyme A methyltransferase, caffeoyl coenzyme A O-methyltransferase, caffeoyl-CoA 3-O-methyltransferase, caffeoyl-CoA-O-methyl transferase 1, caffeoyl-CoA-O-methyl transferase 2, caffeoyl-coenzyme A 3-o-methyltransferase, caffeoyl-coenzyme A O-methyltransferase, CCoAMT, CCoAOMT, CCoAOMT 1, CCoAOMT 2, CCoAOMT-1, CCoAOMT-like, CCoAOMT1, CCoAOMT2, CCoAOMT7, CCOMT, COMT, F6OMT, hi12, More, O-methyltransferase, OMT-15, OMT-17, OMT1, S-adenosyl-L-methionine:trans-caffeoyl-CoA 3-O-methyltransferase, TaCCoAOMT1, trans-caffeoyl-CoA 3-O-methyltransferase, Vp-OMT4, Vp-OMT5

ECTree

     2 Transferases

         2.1 Transferring one-carbon groups

             2.1.1 Methyltransferases

                2.1.1.104 caffeoyl-CoA O-methyltransferase

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Results	in table
4	Activating Compound
910	AA Sequence
6	Application
1	CAS Registry Number
44	Cloned(Commentary)
6	Cofactor
4	Crystallization (Commentary)
5	Expression
21	General Information
9	Inhibitors
23	kcat/KM [mM/s]
54	KM Value [mM]
7	Localization
17	Metals/Ions
27	Molecular Weight [Da]
39	Natural Substrates/ Products (Substrates)
80	Organism
18	Pathway
12	PDB ID
8	pH Optimum
4	pH Range
1	pH Stability
11	pI Value
26	Protein Variants
22	Purification (Commentary)
1	Reaction
1	Reaction Type
71	Reference
75	Source Tissue
73	Specific Activity [micromol/min/mg]
1	Storage Stability
210	Substrates and Products (Substrate)
23	Subunits
112	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
4	Temperature Range [°C]
38	Turnover Number [1/s]

KM Value

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KM Value on EC 2.1.1.104 - caffeoyl-CoA O-methyltransferase

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KM VALUE [mM]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.039

3,4-dihydroxybenzoic acid

Ammi majus

-

pH 7.5, 37°C, in presence of 0.1 mM Co2+

668599

0.0173

5-hydroxy-coniferaldehyde

Triticum aestivum

Q38J50

-

702477

0.00223 - 0.0952

5-hydroxy-feruloyl-CoA

2 entries

0.068

5-hydroxyferulic acid

Ammi majus

-

pH 7.5, 37°C, in presence of 0.1 mM Co2+

668599

0.0007 - 0.0062

5-hydroxyferuoyl-CoA

3 entries

0.039 - 0.088

caffeic acid

3 entries

0.0437

caffeoyl aldehyde

Triticum aestivum

Q38J50

-

702477

0.00024 - 0.64

caffeoyl-CoA

15 entries

0.061 - 0.93

caffeoyl-D-glucose

2 entries

0.0827 - 0.11

cyanidin 3-O-glucoside

2 entries

0.101

epigallocatechin-3-O-gallate

Camellia sinensis

-

pH 6.8, 35°C

734588

0.003 - 0.28

eriodictyol

9 entries

0.00033 - 0.249

quercetagetin

5 entries

0.031 - 0.09159

quercetin

5 entries

0.16

S-adenosyl-L-methionine

Camellia sinensis

-

pH 6.8, 35°C

734588

0.109 - 0.158

tricetin

2 entries

0.00223

5-hydroxy-feruloyl-CoA

Triticum aestivum

-

pH 7.5, 30°C, recombinant enzyme

758087

0.0952

5-hydroxy-feruloyl-CoA

Triticum aestivum

Q38J50

-

702477

0.0007

5-hydroxyferuoyl-CoA

Petroselinum crispum

-

-

485071

0.0022

5-hydroxyferuoyl-CoA

Triticum aestivum

-

pH 7.5, 30°C

734993

0.0062

5-hydroxyferuoyl-CoA

Medicago sativa

-

recombinant enzyme

485067

0.039

caffeic acid

Linum usitatissimum

Q4JHB1

recombinant enzyme, 30°C

706277

0.0688

caffeic acid

Triticum aestivum

Q38J50

-

702477

0.088

caffeic acid

Ammi majus

-

pH 7.5, 37°C, in presence of 0.1 mM Co2+

668599

0.00024

caffeoyl-CoA

Petroselinum crispum

-

-

485071

0.0015

caffeoyl-CoA

Linum usitatissimum

Q4JHB1

recombinant enzyme, 30°C

706277

0.0041

caffeoyl-CoA

Ammi majus

-

pH 7.5, 37°C, in presence of 0.15 mM Mg2+

668599

0.0043

caffeoyl-CoA

Medicago sativa

-

recombinant enzyme

485067

0.02

caffeoyl-CoA

Ammi majus

-

pH 7.5, 37°C, in presence of 0.1 mM Co2+

668599

0.0275

caffeoyl-CoA

Nicotiana tabacum

-

wild-type

485066

0.04774

caffeoyl-CoA

Goniophlebium amoenum

A0A4Y5R9F4

isoform CCoAOMT1, at pH 7.5 and 37°C

758068

0.05114

caffeoyl-CoA

Goniophlebium amoenum

A0A4Y5R9F4

isoform CCoAOMT2, at pH 7.5 and 37°C

758068

0.072

caffeoyl-CoA

Oryza sativa

-

OMT-17, in 10 mM Tris-HCl buffer (pH 7.5), at 37°C

700855

0.083

caffeoyl-CoA

Triticum aestivum

Q38J50

-

702477

0.096

caffeoyl-CoA

Vitis vinifera

Q43237

GST-tagged recombinant enzyme, at pH 8.5 and 30°C

758057

0.112

caffeoyl-CoA

Triticum aestivum

-

pH 7.5, 30°C

734993

0.1123

caffeoyl-CoA

Triticum aestivum

-

pH 7.5, 30°C, recombinant enzyme

758087

0.29

caffeoyl-CoA

Nicotiana tabacum

-

Q61S mutant

485066

0.64

caffeoyl-CoA

Nicotiana tabacum

-

D58A mutant

485066

0.061

caffeoyl-D-glucose

Ammi majus

-

pH 7.5, 37°C, in presence of 0.1 mM Co2+

668599

0.93

caffeoyl-D-glucose

Ammi majus

-

pH 7.5, 37°C, in presence of 0.15 mM Mg2+

668599

0.0827

cyanidin 3-O-glucoside

Vitis vinifera

Q43237

thrombin-cleaved enzyme, at pH 8.5 and 30°C

758057

0.11

cyanidin 3-O-glucoside

Vitis vinifera

Q43237

GST-tagged recombinant enzyme, at pH 8.5 and 30°C

758057

0.003

eriodictyol

Mesembryanthemum crystallinum

Q6YI95

wild-type, pH 7.5, temperature not specified in the publication

734862

0.0225

eriodictyol

Mesembryanthemum crystallinum

Q6YI95

mutant D228A, pH 7.5, temperature not specified in the publication

734862

0.025

eriodictyol

Arabidopsis thaliana

Q9C5D7

mutant G46Y, pH 7.5, 37°C

733869

0.05465

eriodictyol

Goniophlebium amoenum

A0A4Y5R9F4

isoform CCoAOMT2, at pH 7.5 and 37°C

758068

0.063

eriodictyol

Arabidopsis thaliana

Q9C5D7

wild-type, pH 7.5, 37°C

733869

0.08382

eriodictyol

Plagiochasma appendiculatum

A0A0U2YR01

at pH 7.5 and 37°C

757935

0.09636

eriodictyol

Goniophlebium amoenum

A0A4Y5R9F4

isoform CCoAOMT1, at pH 7.5 and 37°C

758068

0.184

eriodictyol

Mesembryanthemum crystallinum

Q6YI95

mutant K157A, pH 7.5, temperature not specified in the publication

734862

0.28

eriodictyol

Arabidopsis thaliana

Q9C5D7

mutant G46Y/W193F/R194M/I195K, pH 7.5, 37°C

733869

0.00033

quercetagetin

Mesembryanthemum crystallinum

Q6YI95

wild-type, pH 7.5, temperature not specified in the publication

734862

0.0014

quercetagetin

Mesembryanthemum crystallinum

Q6YI95

mutant D228A, pH 7.5, temperature not specified in the publication

734862

0.009

quercetagetin

Ammi majus

-

pH 7.5, 37°C, in presence of 0.15 mM Mg2+

668599

0.0098

quercetagetin

Mesembryanthemum crystallinum

Q6YI95

mutant N181A, pH 7.5, temperature not specified in the publication

734862

0.249

quercetagetin

Mesembryanthemum crystallinum

Q6YI95

mutant K157A, pH 7.5, temperature not specified in the publication

734862

0.031

quercetin

Ammi majus

-

pH 7.5, 37°C, in presence of 0.15 mM Mg2+

668599

0.04388

quercetin

Plagiochasma appendiculatum

A0A0U2YR01

at pH 7.5 and 37°C

757935

0.04895

quercetin

Goniophlebium amoenum

A0A4Y5R9F4

isoform CCoAOMT1, at pH 7.5 and 37°C

758068

0.073

quercetin

Ammi majus

-

pH 7.5, 37°C, in presence of 0.1 mM Co2+

668599

0.09159

quercetin

Goniophlebium amoenum

A0A4Y5R9F4

isoform CCoAOMT2, at pH 7.5 and 37°C

758068

0.109

tricetin

Vanilla planifolia

F2YP45, F2YP46

pH 7.5, 30°C

720716

0.158

tricetin

Vanilla planifolia

F2YP45, F2YP46

pH 7.5, 30°C

720716