2.1.1.104: caffeoyl-CoA O-methyltransferase

This is an abbreviated version!
For detailed information about caffeoyl-CoA O-methyltransferase, go to the full flat file.

Reaction

Synonyms

ASCCoAOMT, At4g26220, caffeic acid 3-O-methyltransferase, caffeoyl CoA 3-O-methyltransferase, caffeoyl CoA methyltransferase, caffeoyl CoA methyltransferase 7, caffeoyl CoA O-methyltransferase, caffeoyl CoA-O-methyltransferase, caffeoyl coenzyme A 3-O-methyltransferase, caffeoyl coenzyme A methyltransferase, caffeoyl coenzyme A O-methyltransferase, caffeoyl-CoA 3-O-methyltransferase, caffeoyl-CoA-O-methyl transferase 1, caffeoyl-CoA-O-methyl transferase 2, caffeoyl-coenzyme A 3-o-methyltransferase, caffeoyl-coenzyme A O-methyltransferase, CCoAMT, CCoAOMT, CCoAOMT 1, CCoAOMT 2, CCoAOMT-1, CCoAOMT-like, CCoAOMT1, CCoAOMT2, CCoAOMT7, CCOMT, COMT, F6OMT, hi12, More, O-methyltransferase, OMT-15, OMT-17, OMT1, S-adenosyl-L-methionine:trans-caffeoyl-CoA 3-O-methyltransferase, TaCCoAOMT1, trans-caffeoyl-CoA 3-O-methyltransferase, Vp-OMT4, Vp-OMT5

ECTree

     2 Transferases

         2.1 Transferring one-carbon groups

             2.1.1 Methyltransferases

                2.1.1.104 caffeoyl-CoA O-methyltransferase

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Results	in table
4	Activating Compound
910	AA Sequence
6	Application
1	CAS Registry Number
44	Cloned(Commentary)
6	Cofactor
4	Crystallization (Commentary)
5	Expression
21	General Information
9	Inhibitors
23	kcat/KM [mM/s]
54	KM Value [mM]
7	Localization
17	Metals/Ions
27	Molecular Weight [Da]
39	Natural Substrates/ Products (Substrates)
80	Organism
18	Pathway
12	PDB ID
8	pH Optimum
4	pH Range
1	pH Stability
11	pI Value
26	Protein Variants
22	Purification (Commentary)
1	Reaction
1	Reaction Type
71	Reference
75	Source Tissue
73	Specific Activity [micromol/min/mg]
1	Storage Stability
210	Substrates and Products (Substrate)
23	Subunits
112	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
4	Temperature Range [°C]
38	Turnover Number [1/s]

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Application on EC 2.1.1.104 - caffeoyl-CoA O-methyltransferase

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APPLICATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

agriculture

Populus tremula x Populus alba

Q43095

antisense repression of the enzyme ia an efficient means for genetic engineering of trees with low lignin content

485068

analysis

Medicago sativa

-

downregulating caffeoyl CoA 3-O-methyltransferase in transgenic alfalfa lines neither reduces syringyl lignin units nor wall-bound ferulate, inconsistent with a role for this enzyme in 3-O-methylation of syringyl monolignol precursors and hydroxycinnamic acids

676517

medicine

2 entries

additional information

2 entries

medicine

Curcuma longa

-

plays a role in the biosynthesis of curcuminoids, which are important pharmacologically active metabolites

676373

medicine

Zingiber officinale

-

plays a role in the biosynthesis of gingerols, which are important pharmacologically active metabolites

676373

additional information

Populus tremuloides

-

CCoAOMT and cinnamoyl co-enzyme A reductase are neighboring enzymes, reactions mediated by these two enzymes require different pH environments, indicating that compartmentalization is probably needed for CCoAOMT and cinnamoyl co-enzyme A reductase to function properly in vivo

676451

additional information

Zea mays

-

CCoAOMT is related to lignin biosynthesis, lignin level is lower in leaves of plants subjected to water deficit than in those of well-watered plants, CCoAOMT is highly correlated with caffeic acid/5-hydroxyferulic 3-O-methyltransferase

660255