2.1.1.101: macrocin O-methyltransferase

This is an abbreviated version!
For detailed information about macrocin O-methyltransferase, go to the full flat file.

Reaction

Synonyms

macrocin methyltransferase, S-adenosyl-L-methionine-macrocin O-methyltransferase

ECTree

     2 Transferases

         2.1 Transferring one-carbon groups

             2.1.1 Methyltransferases

                2.1.1.101 macrocin O-methyltransferase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
76	AA Sequence
3	Application
1	CAS Registry Number
1	General Information
18	Inhibitors
11	Ki Value [mM]
6	KM Value [mM]
12	Metals/Ions
4	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
5	Organism
4	Pathway
4	pH Optimum
2	Purification (Commentary)
2	Reaction
1	Reaction Type
5	Reference
1	Specific Activity [micromol/min/mg]
4	Storage Stability
16	Substrates and Products (Substrate)
2	Subunits
2	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]

Systematic Name

print visible entries

print all entries

Systematic Name on EC 2.1.1.101 - macrocin O-methyltransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide Go to Systematic Name Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

SYSTEMATIC NAME

IUBMB Comments

S-adenosyl-L-methionine:macrocin 3'''-O-methyltransferase

Requires Mg2+, Mn2+ or Co2+. The 3-hydroxy group of the 2-O-methyl-6-deoxy-D-allose moiety in the macrolide antibiotic macrosin acts as methyl acceptor, generating tylosin, another macrolide antibiotic. Isolated from the bacterium Streptomyces fradiae. Not identical with EC 2.1.1.102, demethylmacrocin O-methyltransferase.