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1.6.5.5: NADPH:quinone reductase

This is an abbreviated version!
For detailed information about NADPH:quinone reductase, go to the full flat file.

Word Map on EC 1.6.5.5

Reaction

NADPH
+
H+
 + 2 quinone =
NADP+
 + 2 semiquinone

Synonyms

ArsH, Dehydrogenase, reduced nicotinamide adenine dinucleotide (phosphate) (quinone), DT-diaphorase, EC 1.6.99.2, Flavoprotein NAD(P)H:quinone reductase, Menadione oxidoreductase, Menadione reductase, NAD(P)H dehydrogenase, NAD(P)H dehydrogenase (quinone), NAD(P)H menadione reductase, NAD(P)H quinone reductase, NAD(P)H-quinone dehydrogenase, NAD(P)H-quinone oxidoreductase, NAD(P)H-quinone reductase, NAD(P)H:(quinone-acceptor) oxidoreductase, NAD(P)H:menadione oxidoreductase, NAD(P)H:paraquat diaphorase, NAD(P)H:quinone reductase, NADH-menadione reductase, NADH-menaquinone reductase, NADH:quinone reductase, NADPH DT-diaphorase, NADPH quinone acceptor oxidoreductase, NADPH-dependent quinone reductase, NADPH:azodicarbonyl/quinone reductase, NADPH:quinone oxidoreductase, NADPH:quinone reductase, Naphthoquinone reductase, NfsA, nitroreductase A, old yellow enzyme, ORF 17150, p-Benzoquinone reductase, P1-ZCr, P1-zeta-crystallin, P36, PA0660, Phylloquinone reductase, PtoQOR, QAO, Qor, QorA, Quinone reductase, Reduced NAD(P)H dehydrogenase, TcOYE, TmQR1, VAT-1, vesicle amine transport protein-1, Viologen accepting pyridine nucleotide oxidoreductase, Vitamin K reductase, ZCr, zeta-Crystallin, zeta-crystallin homolog protein, zeta-crystallin/NADPH:quinone oxidoreductase, zeta-Crystallin/quinone reductase, Zta1, Zta1p

ECTree

     1 Oxidoreductases
         1.6 Acting on NADH or NADPH
             1.6.5 With a quinone or similar compound as acceptor
                1.6.5.5 NADPH:quinone reductase

Turnover Number

Turnover Number on EC 1.6.5.5 - NADPH:quinone reductase

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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2.8 - 54
1,2-naphthoquinone
3.4 - 90
1,4-benzoquinone
0.7
1,4-dihydroxy-9,10-anthraquinone
-
pH 7.0, 25°C
1 - 80
1,4-Naphthoquinone
1.6
1,8-dihydroxy-9,10-anthraquinone
-
pH 7.0, 25°C
15
2,3,4,6-tetramethyl-1,4-benzoquinone
with NADPH as cosubstrate, at pH 7.5 and 25°C
-
61
2,3-dichloro-1,4-naphthoquinone
-
pH 7.0, 25°C
66
2,3-dimethoxy-5-methyl-1,4-benzoquinone
with NADPH as cosubstrate, at pH 7.5 and 25°C
36.7
2,5-dimethyl-4-benzoquinone
-
pH 7.5, 10°C
41
2,6-dimethoxy-1,4-benzoquinone
with NADPH as cosubstrate, at pH 7.5 and 25°C
51
2,6-dimethyl-1,4-benzoquinone
-
pH 7.0, 25°C
0.28 - 73.27
2-hexenal
11 - 72
2-Hydroxy-1,4-naphthoquinone
56
2-hydroxy-3-methyl-1,4-naphthoquinone
-
pH 7.0, 25°C
54
2-methyl-1,4-benzoquinone
-
pH 7.0, 25°C
3 - 63
2-methyl-1,4-naphthoquinone
0.11
2-nonenal
pH 7, 25°C, wild-type
0.2
2-pentenal
pH 7, 25°C, wild-type
0.16 - 0.97
3-buten-2-one
0.21 - 3.11
3-nonen-2-one
0.2 - 2.66
3-penten-2-one
1.33 - 3.67
4-hydroxy-2-hexenal
1.15
4-hydroxy-2-nonenal
pH 7, 25°C, wild-type
12
5,8-Dihydroxy-1,4-naphthoquinone
-
pH 7.0, 25°C
1.9 - 82
5-hydroxy-1,4-naphthoquinone
0.37
5-Hydroxy-2-methyl-1,4-naphthoquinone
-
pH 7.5
3.8
5-hydroxy-2-methyl-1,4-naphtoquinone
-
pH 7.5
1.4
9,10-anthraquinone-2-sulfonic acid
-
pH 7.0, 25°C
1.13 - 98
9,10-phenanthrenequinone
9.4
anthraquinone-2-sulfonate
-
pH 7.5, 10°C
5
coenzyme Q10
-
pH 7.5, 10°C
0.1
decyl-plastoquinone
-
pH 7.5
35
dibromothymoquinone
-
pH 7.5, 10°C
1.5 - 7.5
dichlorophenolindophenol
25
duroquinone
-
pH 7.5, 10°C
0.03
Ferricytochrome
-
pH 7.5
26
menadione
-
pH 7.5, 10°C
0.01 - 13
NADH
0.12 - 16
NADPH
1.25 - 39.74
propenal
4.2
riboflavin
-
pH 7.0, 25°C
2.5
tetramethyl-1,4-benzoquinone
-
pH 7.0, 25°C