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1.5.8.3: sarcosine dehydrogenase

This is an abbreviated version!
For detailed information about sarcosine dehydrogenase, go to the full flat file.

Word Map on EC 1.5.8.3

Reaction

sarcosine
+
5,6,7,8-tetrahydrofolate
+
electron-transfer flavoprotein
=
glycine
+
5,10-methylenetetrahydrofolate
+
reduced electron-transfer flavoprotein

Synonyms

EC 1.5.99.1, monomethylglycine dehydrogenase, sarcosine N-demethylase, sarcosine:(acceptor) oxidoreductase (demethylating), sarcosine:electron-transfer flavoprotein oxidoreductase (demethylating), SARDH, SDH

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.8 With a flavin or flavoprotein as acceptor
                1.5.8.3 sarcosine dehydrogenase

Disease

Disease on EC 1.5.8.3 - sarcosine dehydrogenase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Brain Neoplasms
Expression of sarcosine metabolism-related proteins according to metastatic site in breast cancer.
Breast Neoplasms
Expression of sarcosine metabolism-related proteins according to metastatic site in breast cancer.
Implications of differences in expression of sarcosine metabolism-related proteins according to the molecular subtype of breast cancer.
Carcinoma
DNA methylation of sarcosine dehydrogenase (SARDH) loci as a prognosticator for renal cell carcinoma.
Carcinoma, Renal Cell
DNA methylation of sarcosine dehydrogenase (SARDH) loci as a prognosticator for renal cell carcinoma.
Cardiomyopathy, Dilated
Anti-mitochondrial antibodies in patients with dilated cardiomyopathy (anti-M7) are directed against flavoenzymes with covalently bound FAD.
Colorectal Neoplasms
Alteration of the tumour suppressor SARDH in sporadic colorectal cancer: a functional and transcriptome profiling-based study.
Heart Diseases
Anti-mitochondrial antibodies (anti-M7) in heart diseases recognize epitopes on bacterial and mammalian sarcosine dehydrogenase.
Liver Neoplasms
Alteration of the tumour suppressor SARDH in sporadic colorectal cancer: a functional and transcriptome profiling-based study.
Lung Neoplasms
Alteration of the tumour suppressor SARDH in sporadic colorectal cancer: a functional and transcriptome profiling-based study.
Myocarditis
Anti-mitochondrial antibodies in patients with dilated cardiomyopathy (anti-M7) are directed against flavoenzymes with covalently bound FAD.
Neoplasm Metastasis
DNA methylation of sarcosine dehydrogenase (SARDH) loci as a prognosticator for renal cell carcinoma.
Expression of sarcosine metabolism-related proteins according to metastatic site in breast cancer.
Neoplasms
Alteration of the tumour suppressor SARDH in sporadic colorectal cancer: a functional and transcriptome profiling-based study.
DNA methylation of sarcosine dehydrogenase (SARDH) loci as a prognosticator for renal cell carcinoma.
Sarcosine Up-Regulates Expression of Genes Involved in Cell Cycle Progression of Metastatic Models of Prostate Cancer.
The role of sarcosine metabolism in prostate cancer progression.
The tumor suppressor activity of the transmembrane protein with epidermal growth factor and two follistatin motifs 2 (TMEFF2) correlates with its ability to modulate sarcosine levels.
TMEFF2 and SARDH cooperate to modulate one-carbon metabolism and invasion of prostate cancer cells.
Pancreatic Neoplasms
Alteration of the tumour suppressor SARDH in sporadic colorectal cancer: a functional and transcriptome profiling-based study.
Prostatic Neoplasms
TMEFF2 and SARDH cooperate to modulate one-carbon metabolism and invasion of prostate cancer cells.
Respiratory Insufficiency
A young adult with sarcosinemia. No benefit from long duration treatment with memantine.
sarcosine dehydrogenase deficiency
Sarcosine dehydrogenase deficiency, the enzyme defect in hypersarcosinemia.
[Sarcosine dehydrogenase deficiency]
Spinal Dysraphism
An association study of 45 folate-related genes in spina bifida: Involvement of cubilin (CUBN) and tRNA aspartic acid methyltransferase 1 (TRDMT1).