1.5.8.3: sarcosine dehydrogenase
This is an abbreviated version!
For detailed information about sarcosine dehydrogenase, go to the full flat file.
Word Map on EC 1.5.8.3
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1.5.8.3
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dimethylglycine
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sarcosinemia
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folate-binding
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dmgdh
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l-pipecolic
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pipox
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medicine
- 1.5.8.3
- dimethylglycine
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sarcosinemia
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folate-binding
- dmgdh
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l-pipecolic
- pipox
- medicine
Reaction
Synonyms
EC 1.5.99.1, monomethylglycine dehydrogenase, sarcosine N-demethylase, sarcosine:(acceptor) oxidoreductase (demethylating), sarcosine:electron-transfer flavoprotein oxidoreductase (demethylating), SARDH, SDH
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Application on EC 1.5.8.3 - sarcosine dehydrogenase
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medicine
medicine
kidney tumors with clinically aggressive features such as a high tumor stage, positive lymph nodes, distant metastases or a previously advanced tumor status exhibit significantly lower methylation of a locus in the SARDH gene. SARDH gene methylation is a significant prognostic factor for recurrence-free survival in renal cell carcinoma patients showing statistical independence from the clinical prognosticators, grade, stage and state of metastasis