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1.5.3.12: dihydrobenzophenanthridine oxidase

This is an abbreviated version!
For detailed information about dihydrobenzophenanthridine oxidase, go to the full flat file.

Word Map on EC 1.5.3.12

Reaction

dihydrochelirubine
+
O2
 +
H+
=
chelirubine
 +
H2O2

Synonyms

DBO, DBOX, DHBP, Oxidase, dihydrobenzophenanthridine

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.3 With oxygen as acceptor
                1.5.3.12 dihydrobenzophenanthridine oxidase

General Information

General Information on EC 1.5.3.12 - dihydrobenzophenanthridine oxidase

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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
-
virus-induced gene silencing to reduce DBOX transcript levels results in a corresponding reduction in sanguinarine, dihydrosanguinarine, and papaverine accumulation in opium poppy roots
metabolism
-
DBOX as a multifunctional oxidative enzyme in benzylisoquinoline alkaloid metabolism, overview. The two-electron oxidation of dihydrosanguinarine catalyzed by dihydrobenzophenanthridine oxidase is the final step in sanguinarine biosynthesis. The formation of the fully conjugated ring system in sanguinarine is similar to the four-electron oxidations of (S)-canadine to berberine and (S)-tetrahydropapaverine to papaverine