1.5.1.49: 1-pyrroline-2-carboxylate reductase [NAD(P)H]
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For detailed information about 1-pyrroline-2-carboxylate reductase [NAD(P)H], go to the full flat file.
Reaction
Synonyms
LhpH
ECTree
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Systematic Name
Systematic Name on EC 1.5.1.49 - 1-pyrroline-2-carboxylate reductase [NAD(P)H]
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L-proline:NAD(P)+ 2-oxidoreductase
The enzyme from the bacterium Colwellia psychrerythraea is involved in trans-3-hydroxy-L-proline metabolism. In contrast to EC 1.5.1.1, 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase [NAD(P)H], which shows similar activity with 1-piperideine-2-carboxylate and 1-pyrroline-2-carboxylate, this enzyme is specific for the latter. While the enzyme is active with both NADH and NADPH, activity is higher with NADPH.