1.5.1.40: 8-hydroxy-5-deazaflavin:NADPH oxidoreductase

This is an abbreviated version!
For detailed information about 8-hydroxy-5-deazaflavin:NADPH oxidoreductase, go to the full flat file.

Word Map on EC 1.5.1.40

1.5.1.40

methanogen

archaea

hydride

8-hydroxy-5-deazaflavins

methanococcus

hydrogenase

vannielii

thermoautotrophicum

methanobacterium

methanobrevibacter

griseus

methanogenesis

stereochemical

smithii

si-face

methane

fulgidus

ch4

Reaction

Synonyms

5-deazaflavin-NADP+ reductase, 8-hydroxy-5-deazaflavin-dependent NADP+ reductase, 8-OH-5-deazaflavin:NADPH oxidoreductase, 8-OH-5dFl:NADPH oxidoreductase, AF0892, F420-dependent NADP oxidoreductase, F420-dependent NADP reductase, F420-dependent NADP+ oxidoreductase, F420:NADPH oxidoreductase, F420H2:NADP oxidoreductase, F420H2:NADP+ oxidoreductase, Fno, Msm_0049, NADP+:F420 oxidoreductase, Tfu-FNO, Tfu_0970

ECTree

1 Oxidoreductases

1.5 Acting on the CH-NH group of donors

1.5.1 With NAD⁺ or NADP⁺ as acceptor

1.5.1.40 8-hydroxy-5-deazaflavin:NADPH oxidoreductase

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Results	in table
94	AA Sequence
1	Application
5	Cloned(Commentary)
10	Cofactor
2	Crystallization (Commentary)
16	General Information
3	General Stability
23	Inhibitors
65	kcat/KM [mM/s]
9	Ki Value [mM]
106	KM Value [mM]
2	Metals/Ions
16	Molecular Weight [Da]
15	Natural Substrates/ Products (Substrates)
2	Organic Solvent Stability
44	Organism
1	Oxidation Stability
21	pH Optimum
4	pH Range
1	pI Value
29	Protein Variants
10	Purification (Commentary)
1	Reaction
36	Reference
6	Source Tissue
9	Specific Activity [micromol/min/mg]
6	Storage Stability
57	Substrates and Products (Substrate)
12	Subunits
47	Synonyms
1	Systematic Name
16	Temperature Optimum [°C]
3	Temperature Range [°C]
2	Temperature Stability [°C]
71	Turnover Number [1/s]

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7.37

1,5-dihydro-8-hydroxy-5-deazaflavin

Methanococcus vannielii

pH 7.0, 20°C

725326

0.0233 - 0.16

1-aminoethylnicotinamide

4 entries

0.0042

1-benzyl-3-acetylpyridine

Thermobifida fusca

Q47RA9

wild-type enzyme, pH 8.0, 25°C

763787

0.0045 - 0.417

1-benzylnicotinamide

3 entries

0.0073

1-ethylnicotinamide

Thermobifida fusca

Q47RA9

wild-type enzyme, pH 8.0, 25°C

763787

0.0233 - 0.103

1-hydroxyethylnicotinamide

4 entries

0.0042 - 0.0118

1-hydroxypropylnicotinamide

2 entries

0.0015 - 0.0098

1-propylnicotinamide

5 entries

6.5

5'-O-methyl-7,8-didemethyl-8-hydroxyflavin

Streptomyces griseus

pH 6.0, 22°C

711315

4.4

5-deaza-8-hydroxyisoalloxazine

Streptomyces griseus

pH 6.0, 22°C

711315

35.57

7,8-didemethyl-8-hydroxy-5-deazariboflavin 5'-phosphate

Streptomyces griseus

pH 6.0, 22°C

711315

175

8-hydroxy-5-deazaflavin

Methanococcus vannielii

pH 7.0, 20°C

725326

10.23

8-hydroxypyrimido[4,5-b]-2,4-(3H,10H)-dione

Streptomyces griseus

pH 6.0, 22°C

711315

12.15

coenzyme F0

Streptomyces griseus

pH 6.0, 22°C

711315

17.22

coenzyme F420

Streptomyces griseus

pH 6.0, 22°C

711315

7.37

NADP+

Methanococcus vannielii

pH 7.0, 20°C

725326

0.11 - 175

NADPH

36 entries

0.7 - 5.3

oxidized coenzyme F420

5 entries

reduced coenzyme F420

Streptomyces griseus

pH 6.0, 22°C

711315