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1.5.1.40: 8-hydroxy-5-deazaflavin:NADPH oxidoreductase

This is an abbreviated version!
For detailed information about 8-hydroxy-5-deazaflavin:NADPH oxidoreductase, go to the full flat file.

Word Map on EC 1.5.1.40

Reaction

reduced coenzyme F420
+
NADP+
=
oxidized coenzyme F420
+
NADPH
+
H+

Synonyms

5-deazaflavin-NADP+ reductase, 8-hydroxy-5-deazaflavin-dependent NADP+ reductase, 8-OH-5-deazaflavin:NADPH oxidoreductase, 8-OH-5dFl:NADPH oxidoreductase, AF0892, F420-dependent NADP oxidoreductase, F420-dependent NADP reductase, F420-dependent NADP+ oxidoreductase, F420:NADPH oxidoreductase, F420H2:NADP oxidoreductase, F420H2:NADP+ oxidoreductase, Fno, Msm_0049, NADP+:F420 oxidoreductase, Tfu-FNO, Tfu_0970

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.1 With NAD+ or NADP+ as acceptor
                1.5.1.40 8-hydroxy-5-deazaflavin:NADPH oxidoreductase

KM Value

KM Value on EC 1.5.1.40 - 8-hydroxy-5-deazaflavin:NADPH oxidoreductase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0028
1,5-dihydro-8-hydroxy-5-deazaflavin
-
pH 7.0, 20°C
2 - 18
1-aminoethylnicotinamide
-
7.4
1-benzyl-3-acetylpyridine
wild-type enzyme, pH 8.0, 25°C
-
4.3 - 9.5
1-benzylnicotinamide
-
25
1-ethylnicotinamide
wild-type enzyme, pH 8.0, 25°C
-
2 - 33
1-hydroxyethylnicotinamide
-
25 - 35
1-hydroxypropylnicotinamide
-
5.7 - 35
1-propylnicotinamide
-
0.0135
5'-O-methyl-7,8-didemethyl-8-hydroxyflavin
-
pH 6.0, 22°C
0.0193
5-deaza-8-hydroxyisoalloxazine
-
pH 6.0, 22°C
0.0155
7,8-didemethyl-8-hydroxy-5-deazariboflavin 5'-phosphate
-
pH 6.0, 22°C
0.008
8-hydroxy-5-deazaflavin
-
pH 7.0, 20°C
0.0775
8-hydroxypyrimido[4,5-b]-2,4-(3H,10H)-dione
-
pH 6.0, 22°C
0.0057
coenzyme F0
-
pH 6.0, 22°C
0.0034 - 0.0625
coenzyme F420
0.0137 - 0.37
NADP+
0.00027 - 500
NADPH
0.0036 - 4
oxidized coenzyme F420
0.0077 - 0.15
reduced coenzyme F420
additional information
additional information
-