1.5.1.33: pteridine reductase
This is an abbreviated version!
For detailed information about pteridine reductase, go to the full flat file.
Word Map on EC 1.5.1.33
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1.5.1.33
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leishmania
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dihydrofolate
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trypanosoma
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antileishmanial
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antifolate
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promastigotes
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leishmaniasis
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trypanosomatids
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pterins
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donovani
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amastigotes
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trypanosomiasis
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dhfr-t
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trypanothione
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reductase-thymidylate
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tarentolae
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dihydrobiopterin
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glucantime
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medicine
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drug development
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pharmacology
- 1.5.1.33
- leishmania
- dihydrofolate
- trypanosoma
-
antileishmanial
- antifolate
- promastigotes
- leishmaniasis
-
trypanosomatids
- pterins
- donovani
- amastigotes
- trypanosomiasis
-
dhfr-t
- trypanothione
-
reductase-thymidylate
- tarentolae
- dihydrobiopterin
-
glucantime
- medicine
- drug development
- pharmacology
Reaction
Synonyms
Atu1130, EC 1.1.1.253, H region methotrexate resistance protein, LaPTR1, LbPTR1, LdPTR1, LmPTR1, LpPTR1, More, NADPH-dependent short-chain dehydrogenase/reductase pteridine reductase, NADPH-dihydropteridine reductase, PruA, pteridine reductase, pteridine reductase 1, pteridine reductase I, PTR1, reductase, dihydropteridine (reduced nicotinamide adenine dinucleotide phosphate), Tb-PR, TbPTR1, tcptr1
ECTree
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Turnover Number
Turnover Number on EC 1.5.1.33 - pteridine reductase
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4.7
7,8-dihydrobiopterin
recombinant wild-type enzyme, pH 6.0, 25°C
2.4
7,8-dihydroneopterin
recombinant wild-type enzyme, pH 6.0, 25°C
2
7,8-dihydromonapterin
recombinant mutant Y161F/Y163F, pH 6.0, 25°C
2.3
7,8-dihydromonapterin
recombinant wild-type enzyme, pH 6.0, 25°C
0.43
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in 50 mM HEPES buffer, pH 7.4, at 25°C
0.44
quinonoid 6,7-dimethyl-7,8-dihydropterin
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in 50 mM HEPES buffer, pH 7.4, at 25°C